N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-2,2,2-trifluoroacetamide CAS 338784-31-9

Purity 97%+In StockPharmaceutical Standards
CAS No.338784-31-9
Molecular FormulaC14H9Cl2F3N2O2
Molecular Weight365.13 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-2,2,2-trifluoroacetamide CAS 338784-31-9 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-2,2,2-trifluoroacetamide.

N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-2,2,2-trifluoroacetamide (CAS 338784-31-9), molecular formula C14H9Cl2F3N2O2 and molecular weight 365.13 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-2,2,2-trifluoroacetamide (C14H9Cl2F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H9Cl2F3N2O2
Molecular Weight365.13 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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