N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methoxybenzamide CAS 338784-55-7
| CAS No. | 338784-55-7 |
| Molecular Formula | C20H16Cl2N2O3 |
| Molecular Weight | 403.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methoxybenzamide.
CATO supplies N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methoxybenzamide (CAS 338784-55-7), a certified reference material (molecular formula C20H16Cl2N2O3, MW 403.26 g/mol) for analytical method development and quality control.
Structurally, N-(1-(2,6-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methoxybenzamide (C20H16Cl2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 403.26 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16Cl2N2O3 |
| Molecular Weight | 403.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1-(1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-3-(pyridin-4-ylmethyl)urea (CAS 400084-76-6)
- 1-(2,4-Dichlorobenzyl)-N-(3-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 320419-67-8)
- 1-(2,4-Dichlorobenzyl)-N-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338977-60-9)
- 1-(2,4-Dichlorobenzyl)-N-(4-methoxyphenyl)-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 242797-38-2)
- N-(1-(3,4-dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-4-methoxybenzamide (CAS 400086-19-3)
- N-(3,4-dichlorobenzyl)-N-(3-(methylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)acetamide (CAS 355406-73-4)
- 2-((1-(2,4-Dichlorobenzyl)piperidin-4-yl)thio)quinoline (CAS 232618-17-6)
- 4-((2,4-Dichlorobenzyl)oxy)-3-iodobenzonitrile (CAS 1706434-38-9)
Recommended Standards
- N-(1-((3,4-Dichlorophenyl)amino)-1-oxo-3-phenylpropan-2-yl)furan-2-carboxamide (CAS 956140-65-1)
- n-(1-((2,5-Dichlorophenyl)amino)-2-oxo-2-(p-tolyl)ethyl)furan-2-carboxamide (CAS 425631-08-9)
- 5-Chloro-1-[(4-chlorophenyl)methyl]-N-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338977-30-3)
- N-(4-(2-((5,7-Dichloro-2-methylquinolin-8-yl)oxy)acetyl)phenyl)acetamide (CAS 853689-23-3)
- Ethyl (E)-2-(2-chloroacetyl)-3-((4-ethoxyphenyl)amino)but-2-enoate (CAS 795290-96-9)
- 2-Bromo-6-methoxy-5-(trifluoromethyl)-1-naphthoic acid (CAS 122670-62-6)
- Praeruptorin B (CAS 81740-07-0)
- 5,6-Dibromonicotinonitrile (CAS 1214384-33-4)
- 4-(2-Fluorobenzoyl)-1-methylpiperidine (CAS 84163-45-1)
- Ethyl 2-(4-(difluoromethyl)-6-(1,3-dimethyl-1H-pyrazol-4-yl)-3-methyl-1H-pyrazolo[3,4-b]pyridin-1-yl)acetate (CAS 1052634-25-9)
- 5-(2-Methylpropyl)-3-[(1H-1,2,3,4-tetrazol-5-yl)amino]cyclohex-2-en-1-one (CAS 1020251-83-5)
- 2-(2-Fluorophenoxy)-N-(isoxazol-4-yl)acetamide (CAS 1396872-13-1)
- 5-(3-Methoxyphenyl)-6,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-4(5H)-one (CAS 1708268-89-6)
- Semaglutide Impurity 184 (CAS CATO-C4X-2226184)
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