N-(3,4-dichlorobenzyl)-N-(3-(methylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)acetamide CAS 355406-73-4
| CAS No. | 355406-73-4 |
| Molecular Formula | C20H16Cl2N2O3 |
| Molecular Weight | 403.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(3,4-dichlorobenzyl)-N-(3-(methylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)acetamide.
N-(3,4-dichlorobenzyl)-N-(3-(methylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)acetamide (CAS 355406-73-4), molecular formula C20H16Cl2N2O3 and molecular weight 403.26 g/mol, is a CATO reference standard with documented purity and traceability.
N-(3,4-dichlorobenzyl)-N-(3-(methylamino)-1,4-dioxo-1,4-dihydronaphthalen-2-yl)acetamide (C20H16Cl2N2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H16Cl2N2O3 |
| Molecular Weight | 403.26 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related N Standards
- 1-(1-(2,6-Dichlorobenzyl)-2-oxo-1,2-dihydropyridin-3-yl)-3-(pyridin-4-ylmethyl)urea (CAS 400084-76-6)
- 1-(2,4-Dichlorobenzyl)-N-(3-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 320419-67-8)
- 1-(2,4-Dichlorobenzyl)-N-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338977-60-9)
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Recommended Standards
- N-(4-(2-((5,7-Dichloro-2-methylquinolin-8-yl)oxy)acetyl)phenyl)acetamide (CAS 853689-23-3)
- tert-Butyl 4-(4-iodophenoxy)piperidine-1-carboxylate (CAS 346617-98-9)
- N-(1-((3,4-Dichlorophenyl)amino)-1-oxo-3-phenylpropan-2-yl)furan-2-carboxamide (CAS 956140-65-1)
- Amisulpride EP Impurity C (CAS 176849-91-5)
- N-(4-Chloro-3-(trifluoromethyl)phenyl)-2-((4-ethyl-5-(pyridin-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 618414-35-0)
- 3-(4-Bromophenyl)-1,4-dimethyl-1h-pyrazol-5-amine (CAS 1152653-72-9)
- 2-Phenyl-4-(4-(2-phenyl-4,5-dihydrooxazol-4-yl)phenyl)oxazole (CAS 24171-38-8)
- NTRC 824 (CAS 1623002-61-8)
- 5,5-Bis(trifluoromethyl)-6,6,7,7,8,8,8-heptafluorooctan-1-ol (CAS 1980040-36-5)
- 1-(4-Bromophenyl)-2-phenylethan-1-ol (CAS 20498-64-0)
- N-Cyclopropyl-N′-hydroxyguanidine hydrochloride (CAS 551935-92-3)
- (1,2-Oxazol-3-yl)methanethiol (CAS 146796-44-3)
- (Z)-hex-4-en-2-yn-1-ol (CAS 75359-52-3)
- Atrial Natriuretic Peptide (ANP)(1-28) Alpha (Human, Ovine, Canine) (CAS 91917-63-4)
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