1-((2-Chloro-6-fluorobenzyl)oxy)-2-(4-chlorophenyl)-1H-benzo[d]imidazole CAS 338791-32-5
| CAS No. | 338791-32-5 |
| Molecular Formula | C20H13Cl2FN2O |
| Molecular Weight | 387.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 1-((2-Chloro-6-fluorobenzyl)oxy)-2-(4-chlorophenyl)-1H-benzo[d]imidazole is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
1-((2-Chloro-6-fluorobenzyl)oxy)-2-(4-chlorophenyl)-1H-benzo[d]imidazole (CAS 338791-32-5) is a high-purity analytical reference standard with the molecular formula C20H13Cl2FN2O and a molecular weight of 387.23 g/mol.
The molecular framework of 1-((2-Chloro-6-fluorobenzyl)oxy)-2-(4-chlorophenyl)-1H-benzo[d]imidazole (C20H13Cl2FN2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H13Cl2FN2O |
| Molecular Weight | 387.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
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Recommended Standards
- (E)-6-Bromo-2-(3,5-dimethoxystyryl)quinazolin-4(3H)-one (CAS 922189-11-5)
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- tert-Butyl 2-(2-bromo-4-nitrophenyl)morpholine-4-carboxylate (CAS 1609462-13-6)
- 3-(3-Bromo-2-oxopropyl)-5,5-diphenylimidazolidine-2,4-dione (CAS 1523570-97-9)
- 2-Methyl-N-(2-propoxybenzyl)-2-propanamine (CAS 866816-82-2)
- 3-oxo-3-(2,2,3,3-tetramethylcyclopropyl)propanenitrile (CAS 1499692-62-4)
- (4-Bromo-5-methoxypyridin-2-yl)methanol (CAS 1454849-84-3)
- 3-(2-Methoxyethyl)-3,4-dihydro-2H-1,3-benzothiazine-2,4-dione (CAS 338401-71-1)
- 6-Iodo-2-methylquinoxaline (CAS 397324-16-2)
- 4'-Bromo-3-chloro-2-methyl-1,1'-biphenyl (CAS 1443352-49-5)
- 3-(piperidin-1-yl)propanoic acid hydrochloride (CAS 14788-15-9)
- Benzo[c][1,2,5]thiadiazol-5-ylmethanamine (CAS 74375-66-9)
- 2-(4-Bromophenyl)-4-(chloromethyl)-5-methyloxazole (CAS 328918-81-6)
- Des-[Gly]31-Semaglutide(x TFA Salt) (CAS 873874-39-6(free base))
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