(E)-6-Bromo-2-(3,5-dimethoxystyryl)quinazolin-4(3H)-one CAS 922189-11-5
| CAS No. | 922189-11-5 |
| Molecular Formula | C18H15BrN2O3 |
| Molecular Weight | 387.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (E)-6-Bromo-2-(3,5-dimethoxystyryl)quinazolin-4(3H)-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (E)-6-Bromo-2-(3,5-dimethoxystyryl)quinazolin-4(3H)-one (CAS 922189-11-5), a certified reference material (molecular formula C18H15BrN2O3, MW 387.23 g/mol) for analytical method development and quality control.
Structurally, (E)-6-Bromo-2-(3,5-dimethoxystyryl)quinazolin-4(3H)-one (C18H15BrN2O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 387.23 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-6-Bromo-2-(3,5-dimethoxystyryl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H15BrN2O3 |
| Molecular Weight | 387.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- Ethyl 3-chloro-4-((2-chloro-4-fluorobenzyl)oxy)-5-ethoxybenzoate (CAS 1706452-96-1)
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- tert-Butyl 2-(2-bromo-4-nitrophenyl)morpholine-4-carboxylate (CAS 1609462-13-6)
- 1-(2-Chloro-6-fluorobenzyl)-4-(2-(4-chlorophenyl)acetyl)-1H-pyrrole-2-carbonitrile (CAS 551931-12-5)
- D-Methionine (CAS 348-67-4)
- N-(6-Amino-3-methyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)acetamide (CAS 19893-78-8)
- 1-CYclopropoxy-3-iodobenzene (CAS 1243459-35-9)
- 1,5-Dichloro-2-fluoro-3-methoxybenzene (CAS 1803834-92-5)
- 3-Acetyl-5,5-dimethyl-4,5-dihydro-1H-pyrazole-4-carbonitrile (CAS 86556-93-6)
- 1-(5-Benzyl-1,3,4-oxadiazol-2-yl)-3-phenylurea (CAS 6756-31-6)
- 3-(4-Fluoro-2-nitrophenoxy)-N-(4-sulfamoylphenyl)thiophene-2-carboxamide (CAS 303152-74-1)
- Methyl 2-(3-(((tert-butoxycarbonyl)amino)methyl)phenyl)acetate (CAS 132691-38-4)
- 2-Hydroxy-6,7,8,9-tetrahydro-11H-pyrido[2,1-b]quinazolin-11-one (CAS 1041382-97-1)
- Polymyxin B nonapeptide (CAS 86408-36-8)
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