2,2-Difluoro-N-phenyl-2-(3-(trifluoromethyl)phenoxy)acetamide CAS 338791-99-4
| CAS No. | 338791-99-4 |
| Molecular Formula | C15H10F5NO2 |
| Molecular Weight | 331.24 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2-Difluoro-N-phenyl-2-(3-(trifluoromethyl)phenoxy)acetamide.
2,2-Difluoro-N-phenyl-2-(3-(trifluoromethyl)phenoxy)acetamide (CAS 338791-99-4) is a high-purity analytical reference standard with the molecular formula C15H10F5NO2 and a molecular weight of 331.24 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 2,2-Difluoro-N-phenyl-2-(3-(trifluoromethyl)phenoxy)acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 331.24 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10F5NO2 |
| Molecular Weight | 331.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
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- Sodium N-(8-((E)-(5-chloro-2-hydroxy-3-sulfophenyl)diazenyl)-7-hydroxynaphthalen-1-yl)acetimidate (CAS 6441-96-9)
- 2-(1,1-difluoropropyl)aniline hydrochloride (CAS 2060034-77-5)
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