2,4-Difluoro-1-(4-iodophenoxy)benzene CAS 851199-61-6

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,4-Difluoro-1-(4-iodophenoxy)benzene.

2,4-Difluoro-1-(4-iodophenoxy)benzene (CAS 851199-61-6) is a high-purity analytical reference standard with the molecular formula C12H7F2IO and a molecular weight of 332.08 g/mol.

2,4-Difluoro-1-(4-iodophenoxy)benzene (C12H7F2IO) contains a hydroxyl group, an ether linkage, fluorine/iodine substitution, an aromatic ring system. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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