(5Z)-5-{[(4-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one CAS 338793-35-4
| CAS No. | 338793-35-4 |
| Molecular Formula | C24H18ClFN2O2 |
| Molecular Weight | 420.86 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(5Z)-5-{[(4-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 338793-35-4), molecular formula C24H18ClFN2O2 and molecular weight 420.86 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of (5Z)-5-{[(4-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (C24H18ClFN2O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (5Z)-5-{[(4-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H18ClFN2O2 |
| Molecular Weight | 420.86 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Z Standards
- (4-Chlorophenyl)(3-(1-((2-fluoro-[1,1'-biphenyl]-4-yl)oxy)ethyl)-1H-pyrazol-1-yl)methanone (CAS 477709-14-1)
- (5Z)-5-{[(2-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 339096-93-4)
- (5Z)-5-{[(3-chlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 339096-94-5)
- 7-(3-Chlorophenyl)-3-({4-oxo-4H-pyrido[1,2-a]pyrimidin-2-yl}methyl)-3H,4H-thieno[3,2-d]pyrimidin-4-one (CAS 1105210-00-1)
- 2-(4-Chlorophenyl)-7-ethoxy-5-(4-nitrophenyl)-3H-benzo[e][1,2,4]triazepine (CAS 444159-02-8)
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- 2-((5-(2-Chlorophenyl)-1,3,4-oxadiazol-2-yl)thio)-N-(2-methoxy-4-nitrophenyl)acetamide (CAS 332160-29-9)
Recommended Standards
- 3-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(3-methylbenzoyl)-1H-pyrazole (CAS 477711-71-0)
- 3-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-(4-methylbenzoyl)-1H-pyrazole (CAS 477711-69-6)
- 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-N-[(phenylcarbamothioyl)amino]acetamide (CAS 1022600-30-1)
- N-[3-(5-chloro-1H-pyrrolo[2,3-b]pyridine-3-carbonyl)-2,4-difluorophenyl]-1,1,2,2,3,3,3-heptadeuteriopropane-1-sulfonamide (CAS 1304096-50-1)
- N-(2,4-difluorophenyl)-2-(3,5-dimethylphenoxy)-2,2-difluoroacetamide (CAS 251097-72-0)
- 2-(3-Oxo-1-(pyridin-2-ylmethyl)piperazin-2-yl)acetic acid (CAS 1041005-47-3)
- 4-(1h-Pyrazol-1-yl)aniline hydrochloride (CAS 913848-94-9)
- 1-[2-Hydroxy-6-(2-phenoxyethoxy)phenyl]ethanone (CAS 61270-14-2)
- 5-Methoxy-3-methyl-4-nitroisoxazole (CAS 84735-85-3)
- 5-(((4-Chlorophenyl)sulfonyl)methyl)-N-hydroxyisoxazole-3-carboxamide (CAS 823220-26-4)
- 4-(4-Methoxyphenyl)-2-phenylthiomorpholine-3,5-dione 1-oxide (CAS 956780-22-6)
- 2-[(pyrazin-2-yl)amino]acetic acid (CAS 27955-54-0)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(m-tolyl)acetamide (CAS 302842-66-6)
- C-Peptide（dog） (CAS 39016-05-2)
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