5-(4-Chlorophenyl)-2-((4-fluorophenyl)thio)nicotinonitrile CAS 338955-19-4
| CAS No. | 338955-19-4 |
| Molecular Formula | C18H10ClFN2S |
| Molecular Weight | 340.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-(4-Chlorophenyl)-2-((4-fluorophenyl)thio)nicotinonitrile (CAS 338955-19-4) is a high-purity analytical reference standard with the molecular formula C18H10ClFN2S and a molecular weight of 340.80 g/mol.
The molecular framework of 5-(4-Chlorophenyl)-2-((4-fluorophenyl)thio)nicotinonitrile (C18H10ClFN2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 5-(4-Chlorophenyl)-2-((4-fluorophenyl)thio)nicotinonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H10ClFN2S |
| Molecular Weight | 340.80 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- 6-Chloro-3-(4-methoxybenzyl)-3,4-dihydro-2H-[1,3]oxazino[5,6-h]quinoline (CAS 50595-08-9)
- 4-Acetylpiperazin-2-one (CAS 17796-61-1)
- 2,5-Dibromo-3,6-dimethylcyclohexa-2,5-diene-1,4-dione (CAS 28293-38-1)
- 2-(1-Methyl-1H-imidazol-5-yl)ethanamine (CAS 644-42-8)
- (3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone (CAS 625377-58-4)
- 1-(2-(5-Bromothiophen-2-yl)ethyl)-3-cyclopropylurea (CAS 1240958-02-4)
- 2-amino-2-[4-(trifluoromethyl)phenyl]ethanol (CAS 473416-36-3)
- Methyl 3-amino-2-[(2-methylphenyl)methyl]propanoate hydrochloride (CAS 1258640-06-0)
- 4-(3-Chlorophenyl)-3h,4h,5h,6h,7h-imidazo[4,5-c]pyridine-6-carboxylic acid (CAS 1192691-11-4)
- (5Alpha,20R)-20-Hydroxypregnan-3-one (CAS 516-58-5)
- Tirzepatide Impurity 46 (CAS CATO-C4X-324046)
Why CATO?
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