(3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone CAS 625377-58-4
| CAS No. | 625377-58-4 |
| Molecular Formula | C23H17F3N2O3S |
| Molecular Weight | 458.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone (CAS 625377-58-4) is a high-purity analytical reference standard with the molecular formula C23H17F3N2O3S and a molecular weight of 458.45 g/mol.
(3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone (C23H17F3N2O3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3-Amino-6-(2,4-dimethoxyphenyl)-4-(trifluoromethyl)thieno[2,3-b]pyridin-2-yl)(phenyl)methanone meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H17F3N2O3S |
| Molecular Weight | 458.45 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1985 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
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Recommended Standards
- 1-[4-[4-(2,3-Dichlorophenyl)piperazin-1-yl]butyl]-7-hydroxy-3,4-dihydro- carbostyril-d8 (CAS 1794789-13-1)
- 4-Methoxy-3-(N-(2-(piperidin-1-yl)-5-(trifluoromethyl)phenyl)sulfamoyl)benzoic acid (CAS 865273-97-8)
- CC-90003 (CAS 1621999-82-3)
- Digalactosyl Diglyceride (CAS 92457-02-8)
- Colesevelam Hydrochloride (CAS 182815-44-7)
- 2-((4-Methyl-1,2,5-oxadiazol-3-yl)oxy)ethanamine (CAS 915924-59-3)
- 9-Ethyl-9H-purine (CAS 5427-23-6)
- tert-butyl 4-fluoro-3-methylbenzoate (CAS 171050-00-3)
- (S)-2-(2-((tert-Butoxycarbonyl)amino)propanamido)acetic acid (CAS 28782-78-7)
- 4-((4-Chloro-2-fluorophenyl)amino)-4-oxobutanoic acid (CAS 904810-52-2)
- 5-((Dimethylamino)methyl)-2,6-dihydroxypyrimidine-4-carboxylic acid (CAS 4116-23-8)
- Narcotoline (CAS 521-40-4)
- 4-Chloro-6-methoxyquinoline-3-carbonitrile (CAS 13669-62-0)
- Tirzepatide Impurity 45 (CAS CATO-C4X-324045)
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