3-((3,5-Dichlorophenyl)sulfonyl)-2-hydroxy-2-methyl-N-(4-(trifluoromethyl)phenyl)propanamide CAS 338956-21-1
| CAS No. | 338956-21-1 |
| Molecular Formula | C17H14Cl2F3NO4S |
| Molecular Weight | 456.26 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
3-((3,5-Dichlorophenyl)sulfonyl)-2-hydroxy-2-methyl-N-(4-(trifluoromethyl)phenyl)propanamide (CAS 338956-21-1) is a high-purity analytical reference standard with the molecular formula C17H14Cl2F3NO4S and a molecular weight of 456.26 g/mol.
The molecular framework of 3-((3,5-Dichlorophenyl)sulfonyl)-2-hydroxy-2-methyl-N-(4-(trifluoromethyl)phenyl)propanamide (C17H14Cl2F3NO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), 3-((3,5-Dichlorophenyl)sulfonyl)-2-hydroxy-2-methyl-N-(4-(trifluoromethyl)phenyl)propanamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H14Cl2F3NO4S |
| Molecular Weight | 456.26 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- 3-{1-[(2,6-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}-1-[3-(trifluoromethyl)phenyl]urea (CAS 400084-72-2)
- 3-{1-[(3,4-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}-1-[3-(trifluoromethyl)phenyl]urea (CAS 338755-47-8)
- 3-(3,5-Dichlorophenyl)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)propanoic acid (CAS 1699437-86-9)
- (3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)-N-(4-(2-pyridylthio)phenyl)formamide (CAS 1023488-73-4)
- N-(2,3-Dichlorophenyl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332376-22-4)
- N-(2,5-Dichlorophenyl)-2-((4-phenyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332376-33-7)
- 1-(3,4-Dichlorophenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 575469-40-8)
- 1-[(2,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-91-0)
Recommended Standards
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-6-bromo-3-fluorobenzoic acid (CAS 2243513-70-2)
- 3-(3,4-Dichlorobenzenesulfonyl)-2-hydroxy-2-methyl-N-[3-(trifluoromethyl)phenyl]propanamide (CAS 338424-41-2)
- 2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-bromo-5-fluorobenzoic acid (CAS 2243507-07-3)
- N-(2-(2,2,2-trifluoroacetamido)ethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338418-19-2)
- 1-(3,3-Difluorocyclopentyl)ethan-1-ol (CAS 1695130-04-1)
- 2-(3-Bromo-4-cyano-2-fluorophenyl)acetic acid (CAS 1806061-82-4)
- Methyl 6-amino-5-cyano-4-(2-fluorophenyl)-2-(methoxymethyl)-4H-pyran-3-carboxylate (CAS 313379-54-3)
- Ethyl 2-(3-amino-4-hydroxyphenyl)acetate (CAS 86818-19-1)
- 2-((2,4-Dichlorobenzyl)thio)-5-methoxypyrimidin-4(3H)-one (CAS 338411-04-4)
- 3-{[(3-Chlorobenzyl)oxy]methyl}piperidinehydrochloride (CAS 1185296-31-4)
- 5-Chloro-2-(5-methylfuran-2-yl)thiazolo[5,4-d]pyrimidin-7-amine (CAS 2232172-56-2)
- 1-Cyclohexyl-3-(1,3-dioxolan-2-yl)-propan-2-one (CAS 1263366-17-1)
- 2-Methylpyrimidine-4-thiol (CAS 33643-86-6)
- Peptide Impurity 82 (CAS 10491-78-8)
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