1-[(2,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione CAS 338418-91-0
| CAS No. | 338418-91-0 |
| Molecular Formula | C23H16Cl2N2O2S |
| Molecular Weight | 455.36 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[(2,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione.
1-[(2,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-91-0) is a high-purity analytical reference standard with the molecular formula C23H16Cl2N2O2S and a molecular weight of 455.36 g/mol.
1-[(2,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (C23H16Cl2N2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[(2,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C23H16Cl2N2O2S |
| Molecular Weight | 455.36 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichlorophenyl Standards
- 1-(3,4-Dichlorophenyl)-2-((5-(pyridin-4-yl)-4-(p-tolyl)-4H-1,2,4-triazol-3-yl)thio)ethanone (CAS 575469-40-8)
- 1-[(2,6-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338419-07-1)
- 1-[(3,4-Dichlorophenyl)methyl]-3'-phenyl-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-94-3)
- 1-Benzyl-3'-(3,4-dichlorophenyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 861211-75-8)
- 3-(2-{[(2,4-dichlorophenyl)methyl]sulfanyl}pyrimidin-4-yl)-1-(4-methylphenyl)-1,4-dihydropyridazin-4-one (CAS 478077-67-7)
- (5Z)-5-{[(3,4-dichlorophenyl)amino]methylidene}-4-(4-fluorophenyl)-1-(4-methoxyphenyl)-2,5-dihydro-1H-pyrrol-2-one (CAS 339012-09-8)
- 5,6-Bis(3,4-dichlorophenyl)-2-(2-hydroxyethyl)-3-oxo-2,3-dihydropyridazine-4-carbonitrile (CAS 75660-46-7)
- 3-{1-[(2,6-dichlorophenyl)methyl]-2-oxo-1,2-dihydropyridin-3-yl}-1-[3-(trifluoromethyl)phenyl]urea (CAS 400084-72-2)
Recommended Standards
- [(E)-2-{1-[3,5-bis(trifluoromethyl)phenyl]-4-(pyridine-4-carbonyl)-1H-1,2,3-triazol-5-yl}ethenyl]dimethylamine (CAS 477858-71-2)
- Methyl 2-(3,4-dichlorobenzamido)-4-methyl-5-(piperidine-1-carbonyl)thiophene-3-carboxylate (CAS 335406-47-8)
- Ethyl 2-((4-(3-(4,5-dichloro-2-methylphenyl)-4,5-dihydro-1H-pyrazol-1-yl)phenyl)sulfonyl)acetate (CAS 35441-14-6)
- 2-({[2,4-dichloro-5-(2-methoxyethoxy)phenyl]carbamoyl}methanesulfonyl)-N,N-diethylacetamide (CAS 341965-10-4)
- 6-Hydroxy-4-methoxybenzofuran-5-carbohydrazide (CAS 34086-81-2)
- Sodium Nicotinate (CAS 54-86-4)
- 2,4,6-Tris(2,4,6-tribromophenoxy)-1,3,5-triazine (CAS 25713-60-4)
- Letermovir impurity 136 (CAS CATO-C4X-2915136)
- Mephenoxalone (CAS 70-07-5)
- 4-(Butylthio)benzaldehyde (CAS 53606-10-3)
- Tert-butyl 2-(1-(cyclopropylimino)-2-phenoxyethyl)hydrazine-1-carboxylate (CAS 1053657-38-7)
- 3,3-dimethylpiperidine-2,5-dione (CAS 2059987-11-8)
- Methyl 3-(3-iodophenyl)-3-oxopropanoate (CAS 260969-02-6)
- Semaglutide impurity 248 (CAS CATO-C4X-2226248)
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