3-(5-Fluoro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine CAS 338956-80-2

Purity 97%+In StockPharmaceutical Standards
CAS No.338956-80-2
Molecular FormulaC18H22FNO3S
Molecular Weight351.44 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(5-Fluoro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine CAS 338956-80-2 chemical structure

Description

3-(5-Fluoro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine (CAS 338956-80-2), molecular formula C18H22FNO3S and molecular weight 351.44 g/mol, is a CATO reference standard with documented purity and traceability.

3-(5-Fluoro-2-methylbenzenesulfonyl)-4,6-dimethyl-2-(2-methylpropoxy)pyridine (C18H22FNO3S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H22FNO3S
Molecular Weight351.44 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms1
Sulfur Atoms1

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