2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide CAS 338957-15-6
| CAS No. | 338957-15-6 |
| Molecular Formula | C24H16ClF3N2O2S |
| Molecular Weight | 488.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide (CAS 338957-15-6) is a high-purity analytical reference standard with the molecular formula C24H16ClF3N2O2S and a molecular weight of 488.91 g/mol.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 488.91 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H16ClF3N2O2S |
| Molecular Weight | 488.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 1-[(2-Chlorophenyl)methyl]-3'-[3-(trifluoromethyl)phenyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-97-6)
- 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 338957-26-9)
- 3'-(4-Chlorophenyl)-1-(3-(trifluoromethyl)benzyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 400081-79-0)
- Ethyl 1-(4-chlorophenyl)-3-methyl-4-((3-(trifluoromethyl)benzyl)amino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 866132-88-9)
- 3-((4-Chlorophenyl)sulfonyl)-1-(2-(2-hydroxyethoxy)ethyl)-2-imino-10-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 607384-44-1)
- (E)-[(4-Chlorophenyl)methoxy]({1-[5-(trifluoromethyl)-3-[3-(trifluoromethyl)phenoxy]pyridin-2-yl]ethylidene})amine (CAS 866132-28-7)
- 3-(2-Chlorophenyl)-4-((3,5-dibromo-2-hydroxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-46-5)
- 3-(3-Chlorophenyl)-4-((3,5-dibromo-2-hydroxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-34-4)
Recommended Standards
- Dibromobis(t-Bu pyridine)nickel (CAS 2640505-89-9)
- N'-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-1-[(3-fluorophenyl)methyl]piperidine-4-carbohydrazide (CAS 478078-99-8)
- 4-{4-[(benzoyloxy)imino]piperidino}-8-chloro-1-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline (CAS 400089-14-7)
- (((2R,3S,4R)-2-(((tert-Butyldimethylsilyl)oxy)methyl)-3,4-dihydro-2H-pyran-3,4-diyl)bis(oxy))bis(tert-butyldimethylsilane) (CAS 121702-69-0)
- 5-Bromo-2-ethyl-1H-pyrrolo[2,3-b]pyridine (CAS 1228666-29-2)
- 5-Bromo-2-isopropylamino-3-nitropyridine (CAS 954228-62-7)
- 2-(p-Tolyl)-2,3-dihydro-1H-imidazo[1,2-b]pyrazole-7-carboxylic acid (CAS 1707603-15-3)
- 1-Hydroxymethyl-4-oxoadamantane (CAS 110874-17-4)
- 4'-O-Methylepicatechin (CAS 97914-20-0)
- Indium(III) octan-1-olate (CAS 106461-03-4)
- 5-(4-Chlorophenyl)-3-(methylthio)-1-phenyl-1H-pyrazole (CAS 80967-24-4)
- 2-[4-(Hydroxymethyl)cyclohex-3-en-1-yl]propan-2-ol (CAS 5502-74-9)
- 6-Fluoro-1H-benzo[d]imidazol-7-amine (CAS 1360940-63-1)
- Liraglutide Impurity 18 TFA Salt (CAS CATO-C4X-199218)
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