2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide CAS 338957-26-9
| CAS No. | 338957-26-9 |
| Molecular Formula | C24H16ClF3N2O2S |
| Molecular Weight | 488.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide.
2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (CAS 338957-26-9) is a high-purity analytical reference standard with the molecular formula C24H16ClF3N2O2S and a molecular weight of 488.91 g/mol.
2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide (C24H16ClF3N2O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(4-(trifluoromethoxy)phenyl)acetamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H16ClF3N2O2S |
| Molecular Weight | 488.91 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 1-[(2-Chlorophenyl)methyl]-3'-[3-(trifluoromethyl)phenyl]-1,2-dihydrospiro[indole-3,2'-[1,3]thiazolidine]-2,4'-dione (CAS 338418-97-6)
- 2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[4-(trifluoromethoxy)phenyl]acetamide (CAS 338957-15-6)
- 3'-(4-Chlorophenyl)-1-(3-(trifluoromethyl)benzyl)spiro[indoline-3,2'-thiazolidine]-2,4'-dione (CAS 400081-79-0)
- Ethyl 1-(4-chlorophenyl)-3-methyl-4-((3-(trifluoromethyl)benzyl)amino)-1H-pyrazolo[3,4-b]pyridine-5-carboxylate (CAS 866132-88-9)
- 3-((4-Chlorophenyl)sulfonyl)-1-(2-(2-hydroxyethoxy)ethyl)-2-imino-10-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 607384-44-1)
- (E)-[(4-Chlorophenyl)methoxy]({1-[5-(trifluoromethyl)-3-[3-(trifluoromethyl)phenoxy]pyridin-2-yl]ethylidene})amine (CAS 866132-28-7)
- 3-(2-Chlorophenyl)-4-((3,5-dibromo-2-hydroxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478254-46-5)
- 3-(3-Chlorophenyl)-4-((3,5-dibromo-2-hydroxybenzylidene)amino)-1H-1,2,4-triazole-5(4H)-thione (CAS 478255-34-4)
Recommended Standards
- 4-{4-[(benzoyloxy)imino]piperidino}-8-chloro-1-(trifluoromethyl)[1,2,4]triazolo[4,3-a]quinoxaline (CAS 400089-14-7)
- Dibromobis(t-Bu pyridine)nickel (CAS 2640505-89-9)
- 5'-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-4,4-dimethyl-hexahydrospiro[cyclohexane-1,3'-pyrrolo[3,4-d][1,2]oxazole]-2,4',6,6'-tetrone (CAS 338410-30-3)
- N'-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carbonyl]-1-[(3-fluorophenyl)methyl]piperidine-4-carbohydrazide (CAS 478078-99-8)
- Amino(1,3,5-trimethyl-1H-pyrazol-4-yl)acetic acid (CAS 1025555-34-3)
- 5-(5-chlorothiophen-2-yl)-1,3,4-thiadiazol-2-amine (CAS 70057-76-0)
- Glycopyrrolate-d5 (CAS CATO-C4X-143114)
- Atrasentan Impurity 183 (CAS CATO-C4X-3347183)
- 3-Cyclopropoxy-5-formylpicolinic acid (CAS 1243344-85-5)
- 3-Chloro-5-nitro-1H-pyrrolo[2,3-b]pyridine (CAS 1190318-05-8)
- 2,4-Dichloro-6-fluorobenzyl bromide (CAS 1807039-84-4)
- Diosmin EP Impurity A (CAS 6100-74-9)
- 1,3-Bis(2,6-di-i-propylphenyl)-4,5-dihydroimidazolium tetrafluoroborate 282109-83-5 1,3-BIS(2,6-DI-I-PROPYLPHENYL)-4,5-DIHYDROIMIDAZOLIUM TETRAFLUOROBORATE;1,3-BIS(2,6-DIISOPROPYLPHENYL)-4,5-DIHYDROIMIDAZOLIUM TETRAFLUOROBORATE;4,5-DIHYDRO-1,3-BIS(2,6-DIISOPROPYLPHENYL)IMIDAZOLIUM TETRAFLUOROBORATE;N,N'-BIS(2,6-DIISOPROPYLPHENYL)DIHYDROIMIDAZOLIUM TETRAFLUOROBORATE;SIPR-HBF4 SC11685 (CAS 282109-83-5)
- Semaglutide impurity 106 (CAS CATO-C4X-2226106)
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