2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3-(trifluoromethyl)phenyl)acetamide CAS 338957-28-1
| CAS No. | 338957-28-1 |
| Molecular Formula | C24H16ClF3N2OS |
| Molecular Weight | 472.91 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 472.91 g/mol gives 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3-(trifluoromethyl)phenyl)acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (CAS 338957-28-1), molecular formula C24H16ClF3N2OS and molecular weight 472.91 g/mol, is a CATO reference standard with documented purity and traceability.
2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3-(trifluoromethyl)phenyl)acetamide (C24H16ClF3N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3-(trifluoromethyl)phenyl)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H16ClF3N2OS |
| Molecular Weight | 472.91 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 1-{2-[5-(3-chlorophenyl)-7-(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-2-yl]thiophen-3-yl}-2,5-dimethyl-1H-pyrrole (CAS 383148-63-8)
- 2-[2-(4-Chlorophenyl)-4-phenyl-1,3-thiazol-5-yl]-N-[3-(trifluoromethyl)phenyl]acetamide (CAS 338957-21-4)
- 3-((4-Chlorophenyl)sulfonyl)-2-imino-1-(3-methoxypropyl)-10-methyl-1H-dipyrido[1,2-a:2',3'-d]pyrimidin-5(2H)-one (CAS 606961-13-1)
- 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-({[(2,4-dichlorophenyl)methyl]sulfanyl}methyl)-4-(propan-2-yl)-4H-1,2,4-triazole (CAS 344274-14-2)
- (4Z)-2-[(4-Chlorophenyl)methoxy]-4-({[3-(trifluoromethyl)phenyl]amino}methylidene)-1,2,3,4-tetrahydroisoquinoline-1,3-dione (CAS 338419-54-8)
- 4-Chlorophenyl 6-bromo-2-(4-chlorophenyl)quinoline-4-carboxylate (CAS 355421-73-7)
- 3-{[(4-chlorophenyl)methyl]sulfanyl}-5-({[(4-chlorophenyl)methyl]sulfanyl}methyl)-4-phenyl-4H-1,2,4-triazole (CAS 344269-64-3)
- 2-(2-(2-Chlorophenyl)-4-phenylthiazol-5-yl)-N-(3,4-dichlorophenyl)acetamide (CAS 338957-24-7)
Recommended Standards
- 2-(2-(4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetyl)-N-phenylhydrazine-1-carbothioamide (CAS 338979-13-8)
- Methyl 2-(benzo[d][1,3]dioxole-5-carboxamido)-5-((3-chlorophenyl)carbamoyl)-4-methylthiophene-3-carboxylate (CAS 335408-34-9)
- Terbutaline impurity 126 (CAS CATO-C4X-1183126)
- 3-Benzyl-1-(3-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-4-hydroxypyridin-2(1H)-one (CAS 551930-55-3)
- N-((1H-benzo[d][1,2,3]triazol-1-yl)methyl)-N-butyl-3-nitroaniline (CAS 129882-03-7)
- 2-Ethyl-3-methylquinoxalin-5-amine (CAS 126987-99-3)
- 3-bromo-2-(bromomethyl)-1-benzofuran (CAS 447402-12-2)
- Azilsartan impurity 141 (CAS CATO-C4X-1096141)
- tert-Butyl (2,5-dioxopyrrolidin-1-yl) adipate (CAS 402958-62-7)
- (E)-3-(5-chloro-2-(trifluoromethyl)phenyl)acrylic acid (CAS 773129-56-9)
- Crisaborole lmpurity 81 (CAS CATO-C4X-202181)
- Methyl 3-methoxy-5-[4-(methoxycarbonyl)phenyl]benzoate (CAS 1820618-09-4)
- 2-(2-Fluoro-4-nitrophenyl)ethanol (CAS 1221119-68-1)
- Liraglutide-d8 Tetratrifluoroacetate (CAS 204656-20-2 (non-labelled, free base))
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