N-(4-(4-chlorophenyl)thiazol-2-yl)-2-((3-(trifluoromethyl)phenyl)thio)acetamide CAS 338957-63-4
| CAS No. | 338957-63-4 |
| Molecular Formula | C18H12ClF3N2OS2 |
| Molecular Weight | 428.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N-(4-(4-chlorophenyl)thiazol-2-yl)-2-((3-(trifluoromethyl)phenyl)thio)acetamide.
N-(4-(4-chlorophenyl)thiazol-2-yl)-2-((3-(trifluoromethyl)phenyl)thio)acetamide (CAS 338957-63-4), molecular formula C18H12ClF3N2OS2 and molecular weight 428.88 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N-(4-(4-chlorophenyl)thiazol-2-yl)-2-((3-(trifluoromethyl)phenyl)thio)acetamide (C18H12ClF3N2OS2) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 428.88 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N-(4-(4-chlorophenyl)thiazol-2-yl)-2-((3-(trifluoromethyl)phenyl)thio)acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H12ClF3N2OS2 |
| Molecular Weight | 428.88 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related N Standards
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- {4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methyl N-(3-methylphenyl)carbamate (CAS 320424-15-5)
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Recommended Standards
- Abacavir EP Impurity B (CAS 1443421-69-9)
- 3-Amino-6-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 15908-70-0)
- Quizalofop-P-Tefuryl (CAS 119738-06-6)
- 3-[1-(3-Chloro-4-fluorobenzoyl)piperidin-4-yl]-4-[(4-methylphenyl)methyl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775385-03-9)
- 1-(4-{[1,1'-biphenyl]-4-yl}-1,3-thiazol-2-yl)-4-(4-methoxyphenyl)piperazine (CAS 685108-06-9)
- Methyl 2-(3-amino-1h-1,2,4-triazol-1-yl)propanoate (CAS 1251110-24-3)
- 2-((1-(tert-Butoxycarbonyl)pyrrolidin-3-yl)thio)acetic acid (CAS 1353987-00-4)
- Metoprolol Impurity 36 (CAS CATO-C4X-136736)
- 4-(4-Ethyl-5-((3-fluorobenzyl)thio)-4H-1,2,4-triazol-3-yl)pyridine (CAS 618426-81-6)
- 8-Methylamino-5--nitroquinolilne (CAS 152810-27-0)
- Methyl 2-methoxy-4-(trifluoromethyl)pyrimidine-5-carboxylate (CAS 887408-51-7)
- prifuroline (CAS 70833-07-7)
- Vitamin A Impurity 30 (CAS CATO-C4X-218730)
- Semaglutide Impurity 152 xTFA (CAS CATO-C4X-2226152)
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