Abacavir EP Impurity B CAS 1443421-69-9
| CAS No. | 1443421-69-9 |
| Molecular Formula | C18H21ClN10O |
| Molecular Weight | 428.88 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Abacavir EP Impurity B (CAS 1443421-69-9), a pharmacopoeial impurity reference standard (molecular formula C18H21ClN10O, MW 428.88 g/mol) used for the identification and quantification of trace impurities in APIs.
Abacavir EP Impurity B (C18H21ClN10O) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H21ClN10O |
| Molecular Weight | 428.88 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 10 |
Related Abacavir Standards
- Abacavir 5’-β-D-GlucuronideDiscontinued. Please see A104985 (CAS 384329-76-4)
- Abacavir 5’-Phosphate (CAS 136470-77-4)
- Abacavir EP Impurity F (CAS 1443421-68-8)
- Abacavir Impurity 13 (CAS CATO-C4X-152713)
- Abacavir Impurity 14 (CAS CATO-C4X-152714)
- Abacavir 3-Hydroxy Impurity (CAS 153064-93-8)
- Abacavir Impurity 20 (CAS 1443421-70-2)
- Abacavir Carboxylate (CAS 384380-52-3)
Recommended Standards
- Quizalofop-P-Tefuryl (CAS 119738-06-6)
- N-(4-(4-chlorophenyl)thiazol-2-yl)-2-((3-(trifluoromethyl)phenyl)thio)acetamide (CAS 338957-63-4)
- Quizalofop-P-tefuryl (CAS 200509-41-7)
- 3-Amino-6-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4(5H)-one (CAS 15908-70-0)
- Nafamostat Impurity 38 (CAS CATO-C4X-133238)
- Alogliptin Impurity 62 (CAS 607376-86-3)
- Oseltamivir EP Impurity G（HCl） (CAS CATO-C4X-172016)
- N-(3-Chloro-4-cyano-5-isothiazolyl)-3-methylbenzenecarboxamide (CAS 159978-14-0)
- 5-Methyl-5H-[1,3]dioxolo[4,5-f]indole-6-carboxylic acid (CAS 790239-59-7)
- (S)-3-(4-Fluorophenyl)morpholine hydrochloride (CAS 1391469-10-5)
- 2-((1-Benzyl-4-chloro-1H-pyrazol-3-yl)oxy)acetonitrile (CAS 139992-00-0)
- 4-Methoxy-3-(1-methyl-1h-pyrazol-3-yl)benzoic acid (CAS 1427379-47-2)
- 2-(Thiophen-2-ylmethoxymethyl)phenylboronic acid (CAS 1256358-81-2)
- Semaglutide impurity 27 (CAS CATO-C4X-222627)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com