2-(((3,5-Dimethylphenyl)thio)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one CAS 338957-77-0
| CAS No. | 338957-77-0 |
| Molecular Formula | C24H19F3N2OS |
| Molecular Weight | 440.48 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-(((3,5-Dimethylphenyl)thio)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 338957-77-0), molecular formula C24H19F3N2OS and molecular weight 440.48 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution, 2-(((3,5-Dimethylphenyl)thio)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 440.48 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-(((3,5-Dimethylphenyl)thio)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C24H19F3N2OS |
| Molecular Weight | 440.48 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dimethylphenyl Standards
- 1-Benzyl-3-((3,4-dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 1326942-25-9)
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- N-(2,4-Dimethylphenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775444-16-0)
- N-(2,5-Dimethylphenyl)-2-[4-(5-ethyl-1,2,4-oxadiazol-3-yl)-1,3-dioxo-1H,2H,3H,5H,6H,7H,8H,9H-pyrimido[1,6-a]azepin-2-yl]acetamide (CAS 1775444-20-6)
- N-(2,5-Dimethylphenyl)-2-((1-(2,4-dimethylphenyl)-1H-tetrazol-5-yl)thio)-2-phenylacetamide (CAS 847840-96-4)
Recommended Standards
- N-(Aminocarbonyl)benzenesulfonamide (CAS 15310-76-6)
- Cyclohexyl 3-(phenylsulfonyl)-3-(4-(trifluoromethyl)phenyl)propanoate (CAS 2376300-24-0)
- N-Cyclopropyl-2-(4-(3-(phenylsulfonyl)propanamido)phenyl)-2H-tetrazole-5-carboxamide (CAS 1396877-76-1)
- Kif15-in-2 (CAS 672926-33-9)
- 2-[(dimethylamino)methyl]-3-hydroxy-3-phenylpropanenitrile (CAS 343776-88-5)
- 1-(3-Bromophenyl)pyrrolidin-2-one (CAS 38348-83-3)
- 2-Amino-1-(2,3-dihydrobenzofuran-5-yl)ethan-1-one (CAS 732961-75-0)
- methyl 5-azaspiro[2.4]heptane-7-carboxylate;hydrochloride (CAS 2207870-15-1)
- 3-(3,4-Dichlorophenyl)-3-(1-oxo-2,3-dihydro-1H-isoindol-2-yl)propanoic acid (CAS 478260-04-7)
- 2-(Chloromethyl)-4-(difluoromethyl)-3-iodo-5-(trifluoromethyl)pyridine (CAS 1807000-92-5)
- 7-Fluoro-1,2,3,4-tetrahydroquinoline-8-carboxylic acid (CAS 1823931-34-5)
- D-Leu26-Tirzepatide (CAS CATO-CPTD788908)
- N-(2,6,8-Trimethylquinolin-4-yl)thiophene-2-carboxamide (CAS 946360-62-9)
- Peptide Impurity 12 (CAS CATO-CPTD788812)
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