4-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-6-(naphthalen-2-ylsulfanyl)pyrimidin-2-amine CAS 478258-46-7
| CAS No. | 478258-46-7 |
| Molecular Formula | C26H27N5S |
| Molecular Weight | 441.59 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-6-(naphthalen-2-ylsulfanyl)pyrimidin-2-amine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-6-(naphthalen-2-ylsulfanyl)pyrimidin-2-amine (CAS 478258-46-7), molecular formula C26H27N5S and molecular weight 441.59 g/mol, is a CATO reference standard with documented purity and traceability.
4-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-6-(naphthalen-2-ylsulfanyl)pyrimidin-2-amine (C26H27N5S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its physicochemical properties are representative of its class; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 4-[4-(2,3-Dimethylphenyl)piperazin-1-yl]-6-(naphthalen-2-ylsulfanyl)pyrimidin-2-amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H27N5S |
| Molecular Weight | 441.59 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 5 |
| Sulfur Atoms | 1 |
Related Dimethylphenyl Standards
- 3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic Acid (CAS 376591-99-0)
- 2-(((3,5-Dimethylphenyl)thio)methyl)-3-(3-(trifluoromethyl)phenyl)quinazolin-4(3H)-one (CAS 338957-77-0)
- N-(2,5-Dimethylphenyl)-2-((1-(2,4-dimethylphenyl)-1H-tetrazol-5-yl)thio)-2-phenylacetamide (CAS 847840-96-4)
- 1-Benzyl-3-((3,4-dimethylphenyl)sulfonyl)-6,7-difluoroquinolin-4(1H)-one (CAS 1326942-25-9)
- N-(2,5-dimethylphenyl)-2-((4-(4-methoxyphenyl)-5-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 333328-64-6)
- Methyl 3-((4-(2,4-dimethylphenyl)piperazin-1-yl)sulfonyl)benzo[b]thiophene-2-carboxylate (CAS 899978-11-1)
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- 2-(3,4-Dimethylphenyl)-4-[3-(4-ethoxyphenyl)-1,2,4-oxadiazol-5-yl]-1,2-dihydrophthalazin-1-one (CAS 1291834-82-6)
Recommended Standards
- n-(Adamantan-1-yl)-2-((3-(3-hydroxypropyl)-4-oxo-3,4-dihydroquinazolin-2-yl)thio)propanamide (CAS 1007763-39-4)
- N-(((9H-fluoren-9-yl)methoxy)carbonyl)-O-(tert-butyldimethylsilyl)-D-serine (CAS 201210-25-5)
- 713139-25-4 Sodium 3-(n-((1r,4r)-4-hydroxycyclohexyl)-4-methylcyclohexanecarboxamido)-5-phenylthiophene-2-carboxylate (CAS 713139-25-4)
- Fmoc-Ser(BSi)-OH (CAS 146346-81-8)
- 9-Xanthenecarbonitrile (CAS 85554-24-1)
- 4,4'-Dichloro-[1,1'-biphenyl]-3,3'-dicarboxylic acid (CAS 70994-42-2)
- 5-(4-(Benzyloxy)-3-methoxyphenyl)-4-(furan-2-carbonyl)-3-hydroxy-1-(2-methoxyethyl)-1H-pyrrol-2(5H)-one (CAS 609797-16-2)
- n-Hexane-1,1,1,6,6,6-d (CAS 32740-20-8)
- 5-(3-Nitrophenyl)isoxazol-3-amine (CAS 1463481-61-9)
- 2-(4-Methylpiperidin-4-yl)acetic acid (CAS 933722-73-7)
- (S)-1-(o-tolyl)propan-1-amine (CAS 779335-88-5)
- Methyl 3-(1-methyl-1H-1,2,4-triazol-5-yl)-3-oxopropanoate (CAS 1007585-93-4)
- (3E)-3-({4-[(6-chloropyridin-3-yl)methoxy]-3-methoxyphenyl}methylidene)-2,3-dihydro-1H-indol-2-one (CAS 861207-72-9)
- MCH-Gene-Overprinted-Polypeptide-14 (rat) (H-4746.0500) (CAS 182917-44-8)
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