3-(4-Chloro-2-methylphenoxy)-5-(trifluoromethyl)picolinonitrile CAS 338960-03-5

Purity 97%+In StockPharmaceutical Standards
CAS No.338960-03-5
Molecular FormulaC14H8ClF3N2O
Molecular Weight312.67 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Chloro-2-methylphenoxy)-5-(trifluoromethyl)picolinonitrile CAS 338960-03-5 chemical structure

Description

CATO supplies 3-(4-Chloro-2-methylphenoxy)-5-(trifluoromethyl)picolinonitrile (CAS 338960-03-5), a certified reference material (molecular formula C14H8ClF3N2O, MW 312.67 g/mol) for analytical method development and quality control.

3-(4-Chloro-2-methylphenoxy)-5-(trifluoromethyl)picolinonitrile (C14H8ClF3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC14H8ClF3N2O
Molecular Weight312.67 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms2

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