1-[(4-chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 478260-55-8 9E-372S CAS 478260-55-8
| CAS No. | 478260-55-8 |
| Molecular Formula | C14H8ClF3N2O |
| Molecular Weight | 312.67 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[(4-chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 478260-55-8 9E-372S (CAS 478260-55-8) is a high-purity analytical reference standard with the molecular formula C14H8ClF3N2O and a molecular weight of 312.67 g/mol.
Structurally, 1-[(4-chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 478260-55-8 9E-372S (C14H8ClF3N2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 312.67 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-[(4-chlorophenyl)methyl]-2-oxo-6-(trifluoromethyl)-1,2-dihydropyridine-3-carbonitrile 478260-55-8 9E-372S meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H8ClF3N2O |
| Molecular Weight | 312.67 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
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Recommended Standards
- 3-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-2,3-dihydro-1H-indol-2-one (CAS 338420-42-1)
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- 9-Benzyl-2-chloro-6-(trifluoromethyl)-9H-purine (CAS 1682-16-2)
- 3-(4-Chloro-2-methylphenoxy)-5-(trifluoromethyl)picolinonitrile (CAS 338960-03-5)
- 2-Methylenepentanoyl chloride (CAS 78450-85-8)
- 2-[4-(4-Chlorobenzenesulfonyl)-5-phenyl-1H-pyrazol-1-yl]-5-[(4-chlorophenyl)sulfanyl]-4-(2,4-dichlorophenyl)-1,3-thiazole (CAS 956627-23-9)
- 1-Butyl-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine (CAS 2213398-77-5)
- (E)-{1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]ethylidene}amino cyclopropanecarboxylate (CAS 477872-55-2)
- N-Methyl-N-phenylbutanamide (CAS 42883-79-4)
- (3S,3AS,6aR)-3a-methyl-3-phenylhexahydro-1H-cyclopenta[c]furan-1-one (CAS 804566-60-7)
- Isavuconazole Impurity 58 (CAS 36776-32-6)
- 1-Chloro-2-(2,2,2-trifluoroethyl)-4-(trifluoromethyl)benzene (CAS 1099597-65-5)
- 2-(Phenylamino)isoquinoline-1,3(2H,4H)-dione (CAS 22177-38-4)
- Semaglutide impurity 33 (CAS CATO-C4X-222633)
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