4-[4-(3-Chlorophenyl)piperazin-1-yl]-2-phenyl-6-[(propan-2-ylsulfanyl)methyl]pyrimidine CAS 338961-52-7
| CAS No. | 338961-52-7 |
| Molecular Formula | C24H27ClN4S |
| Molecular Weight | 439.02 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[4-(3-Chlorophenyl)piperazin-1-yl]-2-phenyl-6-[(propan-2-ylsulfanyl)methyl]pyrimidine is closely related to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[4-(3-Chlorophenyl)piperazin-1-yl]-2-phenyl-6-[(propan-2-ylsulfanyl)methyl]pyrimidine (CAS 338961-52-7), molecular formula C24H27ClN4S and molecular weight 439.02 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[4-(3-Chlorophenyl)piperazin-1-yl]-2-phenyl-6-[(propan-2-ylsulfanyl)methyl]pyrimidine (C24H27ClN4S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-[4-(3-Chlorophenyl)piperazin-1-yl]-2-phenyl-6-[(propan-2-ylsulfanyl)methyl]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H27ClN4S |
| Molecular Weight | 439.02 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
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- 2-((4-(4-Chlorophenyl)-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)-1-(3,4-dihydroxyphenyl)ethanone (CAS 575466-45-4)
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Recommended Standards
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- 3,5-Diiodo-<SC>L</SC>-tyrosine dihydrate (CAS 18835-59-1)
- (5-Phenyl-1H-benzo[d]imidazol-2-yl)methanol (CAS 336616-97-8)
- 6-Amino-3-(bromomethyl)-5-(difluoromethyl)pyridin-2-ol (CAS 1804678-17-8)
- 2-(1H-1,2,4-Triazol-1-yl)nicotinaldehyde (CAS 1374649-96-3)
- N-isopropyl-2,5-dimethylthiophene-3-carboxamide (CAS 1090889-86-3)
- 3-hydroxy-1-methyl-1H-pyrazole-4-carbaldehyde (CAS 1503601-15-7)
- 2-(Methylthio)-5,6-dihydro-4H-1,3-thiazine (CAS 58842-19-6)
- (R/S)-2-(3,4,5-Trimethoxyphenyl)butyric acid (CAS 195202-06-3)
- (S)-(-)-Perillic acid (CAS 23635-14-5)
- Apalutamide Impurity 117 (CAS CATO-C4X-2749117)
- Semaglutide impurity 83 (CAS CATO-C4X-222683)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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