Apalutamide Impurity 117 CAS CATO-C4X-2749117
| CAS No. | CATO-C4X-2749117 |
| Molecular Formula | C8H3F3N4 |
| Molecular Weight | 212.13 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Apalutamide Impurity 117 (CAS CATO-C4X-2749117, C8H3F3N4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Apalutamide Impurity 117 (C8H3F3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 8.0, corresponding to approximately 8 ring(s) or double-bond equivalent(s). With a molecular weight of 212.13 g/mol, it falls into the medium-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Apalutamide Impurity 117 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C8H3F3N4 |
| Molecular Weight | 212.13 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Apalutamide Standards
- Apalutamide Impurity 60 (CAS CATO-C4X-274960)
- Apalutamide Impurity 61 (CAS 1513077-71-8)
- Apalutamide Impurity 106 (CAS CATO-C4X-2749106)
- Apalutamide Impurity 73 (CAS CATO-C4X-274973)
- Apalutamide Impurity 52 (CAS 1803821-36-4)
- Apalutamide Impurity 53 (CAS 1805120-01-7)
- Apalutamide Impurity 44 (CAS 1121056-94-7)
- Apalutamide Impurity 64 (CAS 1211542-14-1)
Recommended Standards
- 7-(Trifluoromethyl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile (CAS 832115-44-3)
- 6-(Trifluoromethyl)imidazo[1,5-a]pyrimidine-8-carbonitrile (CAS 2151834-44-3)
- 2-[3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]ethanol (CAS 1006469-58-4)
- 5-nitro-2-(trifluoromethyl)-1,4-dihydropyridin-4-one (CAS 438554-44-0)
- Rocuronium Impurity 9 (CAS CATO-C4X-12429)
- Sofosbuvir Impurity 102 (CAS CATO-C4X-1052102)
- Iguratimod Impurity 107 (CAS CATO-C4X-1826107)
- Indobufen Impurity N2 (CAS 36691-07-3)
- 6-Iodoimidazo[1,2-a]pyridine-3-carboxylic acid (CAS 1426531-76-1)
- 1-tert-Butyl 5-(N-Succinimidyl) N-Palmitoyl-L-glutamate (CAS 204521-63-1)
- 2-Bromo-4,6-difluorobenzamide (CAS 1805422-78-9)
- 2-(4-Bromo-5-hydroxy-1H-indol-3-yl)acetonitrile (CAS 1227496-65-2)
- 2-((3-Iodophenyl)amino)-1-morpholinopropan-1-one (CAS 1103255-12-4)
- Semaglutide impurity 196 (CAS CATO-C4X-2226196)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com