N-(4-Fluorobenzoyl)-N-(2-hydroxy-1-phenylethyl)thiourea CAS 338963-07-8

Purity 97%+In StockPharmaceutical Standards
CAS No.338963-07-8
Molecular FormulaC16H15FN2O2S
Molecular Weight318.37 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(4-Fluorobenzoyl)-N-(2-hydroxy-1-phenylethyl)thiourea CAS 338963-07-8 chemical structure

Description

The occurrence of N-(4-Fluorobenzoyl)-N-(2-hydroxy-1-phenylethyl)thiourea is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

CATO supplies N-(4-Fluorobenzoyl)-N-(2-hydroxy-1-phenylethyl)thiourea (CAS 338963-07-8), a certified reference material (molecular formula C16H15FN2O2S, MW 318.37 g/mol) for analytical method development and quality control.

Structurally, N-(4-Fluorobenzoyl)-N-(2-hydroxy-1-phenylethyl)thiourea (C16H15FN2O2S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 318.37 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), N-(4-Fluorobenzoyl)-N-(2-hydroxy-1-phenylethyl)thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC16H15FN2O2S
Molecular Weight318.37 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2
Sulfur Atoms1

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