3-Benzyl-8-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane-4-carboxamide CAS 338963-08-9
| CAS No. | 338963-08-9 |
| Molecular Formula | C27H25Cl2F3N4O2 |
| Molecular Weight | 565.41 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-Benzyl-8-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane-4-carboxamide (CAS 338963-08-9), molecular formula C27H25Cl2F3N4O2 and molecular weight 565.41 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-Benzyl-8-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane-4-carboxamide (C27H25Cl2F3N4O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 565.41 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-Benzyl-8-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(4-chlorophenyl)-1-oxa-4,8-diazaspiro[4.5]Decane-4-carboxamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C27H25Cl2F3N4O2 |
| Molecular Weight | 565.41 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related Benzyl Standards
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- 5-Chloro-6-nitrospiro[chroman-2,2'-indole] (CAS 26456-32-6)
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- 4-Chloro-N-{1-[4-methyl-5-({[4-(trifluoromethyl)phenyl]methyl}sulfanyl)-4H-1,2,4-triazol-3-yl]-2-phenylethyl}benzene-1-sulfonamide (CAS 338794-29-9)
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- 2-Chloro-3-(4-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazine-1-carbonyl}piperidin-1-yl)-1,4-dihydronaphthalene-1,4-dione (CAS 439108-72-2)
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- 3-Chloro-2-(4-{[3-(2-phenyl-1,3-thiazol-5-yl)-1H-pyrazol-1-yl]sulfonyl}phenoxy)-5-(trifluoromethyl)pyridine (CAS 318255-89-9)
Recommended Standards
- Rhodium(1+), [(1,2,5,6-η)-1,5-cyclooctadiene][(2R,2'R,5R,5'R)-1,1'-(3,3,4,4-tetrafluoro-1-cyclobutene-1,2-diyl)bis[2,5-dimethylphospholane-κP]]- (CAS 908128-76-7)
- Etravirine Impurity 6 (CAS 1704730-70-0)
- Clobazam Impurity 3 (CAS CATO-C4X-27523)
- 2-(4-((4-Iodophenyl)sulfonyl)piperazin-1-yl)-N-(4-methoxyphenyl)-6-methylpyrimidin-4-amine (CAS 946364-60-9)
- 1,3,5-Trichloro-2-(trifluoromethyl)benzene (CAS 567-59-9)
- (S)-2-amino-2-(3,5-dibromophenyl)ethan-1-ol (CAS 1213424-18-0)
- 4-Methyl-4H-thieno[3,2-b]pyrrole-2-carboxylic acid (CAS 1368165-40-5)
- 1-(2,4-Dimethylphenyl)-2-(3-hydroxypyrrolidin-1-yl)ethan-1-one (CAS 1408130-66-4)
- N-(1H-Benzo[d]imidazol-2-yl)-3,5-dimethyl-1-phenyl-1H-pyrazole-4-carboxamide (CAS 956910-39-7)
- 3-Bromo-8-ethylimidazo[1,2-a]pyridine (CAS 1392211-06-1)
- Acenocoumarol Impurity 16 (CAS 64191-21-5)
- Methyl (R)-4-(1-aminoethyl)benzoate hydrochloride (CAS 1097196-96-7)
- Benzenepropanamide, α-amino-N-[3-(1H-imidazol-1-yl)propyl]-, dihydrochloride, (αS)- (CAS 1573006-37-7)
- Tirzepatide Impurity 49 (CAS CATO-C4X-324049)
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