6-(2-Chlorophenyl)-2-(4-methoxyphenoxy)-4-(trifluoromethyl)pyridine-3-carbonitrile CAS 338963-49-8
| CAS No. | 338963-49-8 |
| Molecular Formula | C20H12ClF3N2O2 |
| Molecular Weight | 404.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C20H12ClF3N2O2, 6-(2-Chlorophenyl)-2-(4-methoxyphenoxy)-4-(trifluoromethyl)pyridine-3-carbonitrile contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 404.77 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
CATO supplies 6-(2-Chlorophenyl)-2-(4-methoxyphenoxy)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-49-8), a certified reference material (molecular formula C20H12ClF3N2O2, MW 404.77 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-(2-Chlorophenyl)-2-(4-methoxyphenoxy)-4-(trifluoromethyl)pyridine-3-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H12ClF3N2O2 |
| Molecular Weight | 404.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenyl Standards
- 2-[4-(4-Chlorophenyl)-2-methyl-3-oxo-1,2,4-oxadiazolidin-5-yl]-N-(2-methyl-4-nitrophenyl)acetamide (CAS 478077-80-4)
- 1-(4-Chlorophenyl)-3-(9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)urea (CAS 922713-75-5)
- N-(4-chlorophenyl)-2-(2-(2,3-dichlorophenoxy)acetyl)hydrazine-1-carbothioamide (CAS 1024342-88-8)
- 6-(2-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-48-7)
- 6-(4-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-45-4)
- 2-(2-(2-Chlorophenyl)-4-oxoquinazolin-3(4H)-yl)ethyl benzoate (CAS 90094-98-7)
- 3-(2-Chlorophenyl)-5-methyl-N-(4-phenoxyphenyl)isoxazole-4-carboxamide (CAS 309951-81-3)
- 5-(3-(4-Chlorophenyl)benzo[c]isoxazol-5-yl)-5-methyl-2-phenyl-1,2,4-triazolidin-3-one (CAS 337920-28-2)
Recommended Standards
- 5-(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)-3-[3-(trifluoromethyl)phenyl]-1,2,4-oxadiazole (CAS 477712-52-0)
- 6-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(4-methoxyphenyl)pyrazolo[1,5-a]pyrimidine (CAS 338420-94-3)
- (E)-1-(4-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)-3-(pyridin-4-yl)prop-2-en-1-one (CAS 338415-74-0)
- Ethyl 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-2-{[(5-methylfuran-2-yl)methyl]carbamoyl}acetate (CAS 478257-84-0)
- 5-Nitro-2-propylbenzo[d]oxazole (CAS 861211-72-5)
- 2-Hydrazinyl-6-nitroquinoline-4-carboxylic acid (CAS 55764-58-4)
- Ethyl 2-(difluoromethyl)-6-fluoroimidazo[1,2-a]pyridine-3-carboxylate (CAS 2451256-53-2)
- (Chloromethyl)diethoxy(methyl)silane (CAS 2212-10-4)
- 1-Amino-3-(4-bromophenoxy)propan-2-ol (CAS 112169-36-5)
- 2-(3-(N,N-bis(4-methoxybenzyl)sulfamoyl)-1H-pyrazol-1-yl)-2-methylpropanoic acid (CAS 2281768-53-2)
- 4-Phenylazepane (CAS 73252-01-4)
- 7-Bromo-1H,2h,3h-pyrrolo[3,2-c]pyridin-2-one (CAS 1788054-65-8)
- 6-Chloro-2,3,4,9-tetrahydro-1H-carbazol-1-amine hydrochloride (CAS 1443424-91-6)
- Gastric Inhibitory Polypeptide (human) (CAS 100040-31-1)
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