6-(2-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile CAS 338963-48-7
| CAS No. | 338963-48-7 |
| Molecular Formula | C20H12ClF3N2S |
| Molecular Weight | 404.84 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies 6-(2-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-48-7), a certified reference material (molecular formula C20H12ClF3N2S, MW 404.84 g/mol) for analytical method development and quality control.
The molecular framework of 6-(2-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile (C20H12ClF3N2S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 6-(2-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H12ClF3N2S |
| Molecular Weight | 404.84 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- 6-(4-Chlorophenyl)-2-[(4-methylphenyl)sulfanyl]-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 338963-45-4)
- 2-(2-(2-Chlorophenyl)-4-oxoquinazolin-3(4H)-yl)ethyl benzoate (CAS 90094-98-7)
- 3-(2-Chlorophenyl)-5-methyl-N-(4-phenoxyphenyl)isoxazole-4-carboxamide (CAS 309951-81-3)
- 5-(3-(4-Chlorophenyl)benzo[c]isoxazol-5-yl)-5-methyl-2-phenyl-1,2,4-triazolidin-3-one (CAS 337920-28-2)
- 1-(4-Chlorophenyl)-3-(9-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-9H-purin-6-yl)urea (CAS 922713-75-5)
- 3-(4-((2-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(furan-2-yl)pyridazine (CAS 1021099-83-1)
- 2-[4-(4-Chlorophenyl)-2-methyl-3-oxo-1,2,4-oxadiazolidin-5-yl]-N-(2-methyl-4-nitrophenyl)acetamide (CAS 478077-80-4)
- 1-(2-Chlorophenyl)-N-(3-phenylpropyl)-5-(1H-pyrrol-1-yl)-1H-pyrazole-4-carboxamide (CAS 1206997-67-2)
Recommended Standards
- (2E)-3-Amino-3-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-cyano-N-methylprop-2-enethioamide (CAS 338422-38-1)
- N-(2-Chloro-4-nitrophenyl)-2-((5-(o-tolyl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 332357-70-7)
- Choline Fenofibrate Impurity 26 (CAS 1797121-54-0)
- 4-((3-Chloro-4-fluorophenyl)amino)-6-((pyridin-3-ylmethyl)amino)-1,7-naphthyridine-3-carbonitrile (CAS 871307-18-5)
- N-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)thiophene-2-carboxamide (CAS 288312-08-3)
- 1-Methyl-5-(3-nitrophenyl)-1H-pyrazole (CAS 573711-98-5)
- 3-Cyclopropoxy-5-(dimethylamino)pyridine-4-sulfonamide (CAS 1243399-61-2)
- 4-(trifluoromethyl)pyridazin-3-amine (CAS 1167417-13-1)
- Atrasentan Impurity 207 (CAS CATO-C4X-3347207)
- N-Carbamimidoyl-1H-pyrrole-2-carboxamide (CAS 172461-06-2)
- (2-Ethyl-6-(trifluoromethyl)pyridin-4-yl)boronic acid (CAS 2225170-32-9)
- 6-bromopyrrolo[2,1-f][1,2,4]triazine-2,4-diamine (CAS 1824200-86-3)
- 6-O-[3-Acetamido-3-deoxy-α-D-glucopyranosyl]-4-O-(6-acetamido-3,6-dideoxy-3-nitrohexopyranosyl)-N,N-diacetyl-2-deoxy-D-streptamine (CAS 20971-00-0)
- Semaglutide impurity 41 (CAS CATO-C4X-222641)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com