2-(2-Chlorophenoxy)-5-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile CAS 338964-53-7
| CAS No. | 338964-53-7 |
| Molecular Formula | C19H10ClF3N2O |
| Molecular Weight | 374.74 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 2-(2-Chlorophenoxy)-5-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 374.74 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO supplies 2-(2-Chlorophenoxy)-5-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 338964-53-7), a certified reference material (molecular formula C19H10ClF3N2O, MW 374.74 g/mol) for analytical method development and quality control.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H10ClF3N2O |
| Molecular Weight | 374.74 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chlorophenoxy Standards
- 2-(3-Chlorophenoxy)-6-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 303152-82-1)
- 2-(4-Chlorophenoxy)-5-[3-(trifluoromethyl)phenyl]pyridine-3-carbonitrile (CAS 338964-55-9)
- 2-(4-Chlorophenoxy)-6-phenyl-4-(trifluoromethyl)nicotinonitrile (CAS 338749-45-4)
- 3-(4-(2-Chlorophenoxy)piperidine-1-carboxamido)benzoic acid (CAS 1058702-87-6)
- 5-(3-Chlorophenoxy)-1,3-diphenyl-1H-pyrazole-4-carbaldehyde (CAS 956368-13-1)
- 2-((5-((4-Chlorophenoxy)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 332911-17-8)
- 2-(4-Chlorophenoxy)-N-(4-(4-methoxyphenyl)thiazol-2-yl)acetamide (CAS 330201-57-5)
- 2-(4-Chlorophenoxy)-2-((5-chloropyrimidin-2-yl)oxy)-1-phenylethanone (CAS 88350-63-4)
Recommended Standards
- 4-[(4-Chlorophenyl)methyl]-2-(2,6-difluorophenyl)-3,5-dioxo-2,3,4,5-tetrahydro-1,2,4-triazine-6-carbonitrile (CAS 672951-30-3)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(3,5-dimethoxyphenyl)acetamide (CAS 477890-09-8)
- 2-Chloro-8-hydroxy-9,10-dioxo-9,10-dihydroanthracene-1,4-diyl diacetate (CAS 87712-28-5)
- 2-Chloro-5-hydroxy-9,10-dioxo-9,10-dihydroanthracene-1,4-diyl diacetate (CAS 87712-27-4)
- 1,1,3-Trioxo-2-(oxolan-2-ylmethyl)-2,3-dihydro-1,2-benzothiazole-6-carboxylic acid (CAS 1040074-58-5)
- (R)-2-(2-bromo-6-chlorophenyl)-2-(methylamino)ethan-1-ol (CAS 1335570-84-7)
- 5,7-bis(trifluoromethyl)-1,8-naphthyridine-2-carboxylic acid (CAS 1379526-94-9)
- Ethyl 3-bromo-1-propyl-1H-pyrazole-4-carboxylate (CAS 1707602-96-7)
- N-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-2-((4-ethyl-5-(furan-2-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 573696-56-7)
- N-(4-Chloro-2-methoxyphenyl)formamide (CAS 74702-42-4)
- tert-Butyl 7-oxo-1,4-oxazepane-4-carboxylate (CAS 777078-01-0)
- 3,6-Diethylpyrazin-2-amine (CAS 74152-23-1)
- 1-Amino-n-butylcyclohexane-1-carboxamide (CAS 1016500-88-1)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788694)
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