2-(2-Fluorobenzyl)malononitrile CAS 338965-16-5
| CAS No. | 338965-16-5 |
| Molecular Formula | C10H7FN2 |
| Molecular Weight | 174.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(2-Fluorobenzyl)malononitrile.
CATO supplies 2-(2-Fluorobenzyl)malononitrile (CAS 338965-16-5), a certified reference material (molecular formula C10H7FN2, MW 174.17 g/mol) for analytical method development and quality control.
The molecular framework of 2-(2-Fluorobenzyl)malononitrile (C10H7FN2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 2-(2-Fluorobenzyl)malononitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C10H7FN2 |
| Molecular Weight | 174.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Fluorobenzyl Standards
- 4-Fluorobenzyl magnesium chloride (CAS 1643-73-8)
- 1-(2-Fluorobenzyl)-1H-imidazole (CAS 102993-74-8)
- 1-(3-Fluorobenzyl)-1H-imidazole (CAS 109485-43-0)
- 1-(4-Fluorobenzyl)-1H-imidazole (CAS 56643-73-3)
- 1-(4-Fluorobenzyl)-1H-pyrazole (CAS 500367-31-7)
- 5-(4-Fluorobenzyl)-3,4-dihydro-2H-pyrrole (CAS 113700-23-5)
- 1-(4-Fluorobenzyl)-2,5-dihydro-1H-pyrrole (CAS 954416-86-5)
- Ethyl(4-fluorobenzyl)sulfane (CAS 99224-74-5)
Recommended Standards
- 1-(Fluoromethyl)-4-oxocyclohexane-1-carboxylic acid (CAS 2228392-30-9)
- 2-(3-Fluorophenyl)pyrimidine (CAS 68049-16-1)
- 1-(Fluoromethyl)-2-oxabicyclo[2.2.1]heptane-4-carboxylic acid (CAS 2460755-32-0)
- 2-(4-Fluoro-1H-indol-3-yl)acetonitrile (CAS 89434-04-8)
- 3-Bromo-5-methyl-2-(4H-1,2,4-triazol-4-yl)pyridine (CAS 1123169-57-2)
- Trimetazidine Impurity 2 (CAS 93152-26-2)
- 6,8-Dioxabicyclo[3.2.1]Octan-4-yl benzoate (CAS 1214104-67-2)
- tert-Butyl (2S,4R)-2-formyl-4-methylpyrrolidine-1-carboxylate (CAS 2869831-95-6)
- 3-Chloro-4-methylsulfanyl-benzaldehyde (CAS 38125-81-4)
- Methyl 2,5-dichloro-6-formylnicotinate (CAS 2750929-48-5)
- 5,7-Dimethyl-1-(2-(o-tolyloxy)ethyl)indoline-2,3-dione (CAS 883279-96-7)
- Olopatadine Impurity 51 (CAS 113806-01-2)
- 5-(Furan-2-yl)-n-methyl-1,2-oxazole-3-carboxamide (CAS 1343867-60-6)
- D-allo-Thr7-Semaglutide (CAS CATO-C4X-2226242)
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