Olopatadine Impurity 51 CAS 113806-01-2
| CAS No. | 113806-01-2 |
| Molecular Formula | C22H25NO3 |
| Molecular Weight | 351.44 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 351.44 g/mol gives Olopatadine Impurity 51 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Olopatadine Impurity 51 (CAS 113806-01-2) is a certified pharmaceutical impurity reference standard with the molecular formula C22H25NO3 and a molecular weight of 351.44 g/mol.
Based on its molecular formula C22H25NO3, Olopatadine Impurity 51 contains a steroid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 351.44 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H25NO3 |
| Molecular Weight | 351.44 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1989 |
| Nitrogen Atoms | 1 |
Related Olopatadine Standards
- Olopatadine Impurity 49 (CAS CATO-C4X-171849)
- Olopatadine Impurity 69 (CAS CATO-C4X-171869)
- Olopatadine Impurity 73 (CAS CATO-C4X-171873)
- Olopatadine Impurity N1 (CAS 203188-31-2)
- Olopatadine USP Related Compound B (CAS 173174-07-7)
- Olopatadine Impurity 52 (CAS 949141-21-3)
- Olopatadine-d3 N-Oxide (CAS 1246832-94-9)
- Olopatadine Amide (CAS 872041-02-6)
Recommended Standards
- Methylene blue /Methylthioninium Chloride Impurity 23 (CAS CATO-C4X-189623)
- Bisoprolol Impurity 109 (CAS 87844-84-6)
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- Quetiapine Fumarate EP Impurity V (CAS 2204369-14-0)
- Dabigatran Impurity 18 (CAS 1307233-93-7)
- Lomefloxacin Impurity 17 (CAS CATO-C4X-207317)
- Flurbiprofen Impurity 165 (CAS CATO-C4X-1444165)
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- 7-Hydroxybenzo[b]thiophene-5-carboxylic acid (CAS 1221448-81-2)
- 4-(Butylamino)picolinamide (CAS 1153325-95-1)
- 2,6-Difluoro-3-iodobenzonitrile (CAS 1447606-20-3)
- Phenyl(2-(phenylsulfonyl)ethyl)sulfane (CAS 29290-71-9)
- N-(2-(2,4-Dioxo-1,4-dihydrothieno[3,2-d]pyrimidin-3(2H)-yl)ethyl)-4-methylthiazole-5-carboxamide (CAS 2034416-80-1)
- Semaglutide impurity 276 (CAS CATO-C4X-2226276)
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