6-Chloro-2-(((2,6-dichlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one CAS 338965-69-8
| CAS No. | 338965-69-8 |
| Molecular Formula | C22H15Cl3N2OS |
| Molecular Weight | 461.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 461.79 g/mol gives 6-Chloro-2-(((2,6-dichlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
6-Chloro-2-(((2,6-dichlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 338965-69-8) is a high-purity analytical reference standard with the molecular formula C22H15Cl3N2OS and a molecular weight of 461.79 g/mol.
Structurally, 6-Chloro-2-(((2,6-dichlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one (C22H15Cl3N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 461.79 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-2-(((2,6-dichlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H15Cl3N2OS |
| Molecular Weight | 461.79 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 3-(4-Chloro-2-methylphenyl)-2-{[(2,6-dichlorophenyl)sulfanyl]methyl}-3,4-dihydroquinazolin-4-one (CAS 338959-62-9)
- 6-Chloro-2-(((2,5-dichlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 338965-73-4)
- (3Z)-3-{[(3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl)amino]methylidene}-1-(pyrimidin-2-yl)pyrrolidin-2-one (CAS 338954-33-9)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}phenyl 3-(trifluoromethyl)benzoate (CAS 338978-06-6)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(1,2-dihydronaphtho[2,1-b]furan-2-yl)methanone (CAS 478064-60-7)
- 3-Chloro-5-fluorobenzyl 4-(3-oxo-3-(2-oxo-2,3-dihydrobenzo[d]oxazol-6-yl)propyl)piperazine-1-carboxylate (CAS 1144036-48-5)
- (4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)(4-methyl-2-phenylpyrimidin-5-yl)methanone (CAS 338399-42-1)
- 4-(4-(2-((2-Chloro-4-(trifluoromethyl)phenyl)amino)ethyl)-5-methyl-4H-1,2,4-triazol-3-yl)-1-phenyl-1H-pyrazol-5-amine (CAS 957040-55-0)
Recommended Standards
- 3-((4-Bromophenyl)thio)-3-(4-chlorophenyl)-1-(4-methoxyphenyl)propan-1-one (CAS 329779-48-8)
- Lactofen (CAS 77501-63-4)
- Methyl 3-(2-chlorophenyl)-5-(1-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-4-yl)isoxazole-4-carboxylate (CAS 318949-18-7)
- N-(4-(4-chlorophenyl)thiazol-2-yl)-2-((2,3-dichlorophenyl)sulfonyl)acetamide (CAS 338965-87-0)
- N-(1-(1-Ethyl-1H-benzo[d]imidazol-2-yl)ethyl)-3-nitroimidazo[1,2-a]pyridin-2-amine (CAS 1797066-77-3)
- 2,2'-(5-(tert-Butyl)-1,3-phenylene)bis(4,4-dimethyl-4,5-dihydrooxazole) (CAS 915032-89-2)
- 3-Chloro-4-(4-iodophenoxy)aniline (CAS 84865-98-5)
- 4,6-Dichloro-2-(trifluoromethyl)quinazoline (CAS 746671-32-9)
- 2-(4-tert-Butylphenyl)-3,4-dihydro-5H-1,3,4-benzotriazepin-5-one (CAS 1374509-71-3)
- (4-Methoxyphenyl)(8-methyl-[1,3]dioxolo[4,5-g]quinolin-7-yl)methanone (CAS 866051-32-3)
- Ethyl 3-[(4-Chlorophenyl)(hydroxy)methyl]isoxazole-4-carboxylate (CAS 2006277-36-5)
- Ethyl 5-(2-aminoethyl)-1,2,4-oxadiazole-3-carboxylate hydrochloride (CAS 890713-72-1)
- 1-(Benzoylamino)cyclohexanecarboxylic acid (CAS 107521-99-3)
- Semaglutide impurity 237 (CAS CATO-C4X-2226237)
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