6-Chloro-2-(((3-chlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one CAS 338965-74-5
| CAS No. | 338965-74-5 |
| Molecular Formula | C22H16Cl2N2OS |
| Molecular Weight | 427.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
6-Chloro-2-(((3-chlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one (C22H16Cl2N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
6-Chloro-2-(((3-chlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 338965-74-5) is a high-purity analytical reference standard with the molecular formula C22H16Cl2N2OS and a molecular weight of 427.35 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-2-(((3-chlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H16Cl2N2OS |
| Molecular Weight | 427.35 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 6-Chloro-2-(((4-chlorophenyl)thio)methyl)-3-(o-tolyl)quinazolin-4(3H)-one (CAS 338965-68-7)
- 3-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-1-(3-chlorobenzyl)-1H-pyrazole (CAS 477711-61-8)
- 3-{3-[(2-chloro-6-fluorophenyl)methoxy]phenyl}-1-[(3-chlorophenyl)methyl]-1H-pyrazole (CAS 477712-58-6)
- 4-Chloro-N-[2-(6-chloro-4-trifluoromethyl-pyridine-2-sulfonyl)-ethyl]-benzamide (CAS 1311280-14-4)
- 1-Chloro-2-methylpentane (CAS 14753-05-0)
- (E)-3-(2-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)vinyl)-N-(4-chlorophenyl)-1H-pyrazole-1-carboxamide (CAS 321534-56-9)
- 3-Chloro-N-(3-iodophenyl)-6-methylbenzo[b]thiophene-2-carboxamide (CAS 332381-05-2)
- 2-((1-Benzyl-5-chloro-1H-benzo[d]imidazol-2-yl)thio)-N-(2-cyano-3-methylbutan-2-yl)acetamide (CAS 765283-00-9)
Recommended Standards
- 4-(Allylamino)-2-((2,6-dichlorobenzyl)thio)-6-phenylpyrimidine-5-carbonitrile (CAS 303985-77-5)
- 2-(4-Fluorophenyl)-6-methyl-4-(3-(trifluoromethyl)phenyl)-1,2-dihydrodipyrazolo[3,4-b:3',4'-d]pyridin-3(6H)-one (CAS 635324-72-0)
- N-Biotinyl p-aminophenyl arsinic acid, 97% (CAS 212391-23-6)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-spiro[2H-1-benzopyran-2,4'-piperidine]-1'-carboxylic acid 1,1-dimethylethyl ester (CAS 911228-63-2)
- Methyl 2-(5-methylisoxazole-4-carboxamido)benzoate (CAS 724436-21-9)
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- N-(4-fluorobenzoyl)-beta-alanine (CAS 440341-64-0)
- [(4-chlorophenyl)methyl][2-(diethylamino)ethyl]amine (CAS 84434-83-3)
- 3-Benzyl-2-methylquinolin-4(1H)-one (CAS 124443-78-3)
- 2-(5-Hydroxy-1,3-dihydroisobenzofuran-1-yl)acetic acid (CAS 1956327-38-0)
- 3-Bromo-N-((1-methyl-1h-pyrazol-5-yl)methyl)aniline (CAS 1156714-01-0)
- 5-Methyl-2-(methylamino)-3-(phenylsulfonyl)pyrazolo[1,5-a]pyrimidin-7(4h)-one (CAS 1334489-92-7)
- 5-Bromo-7-fluoro-2,3-dihydro-1h-indole-2,3-dione (CAS 874830-75-8)
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