6-Chloro-3-(o-tolyl)-2-(((3-(trifluoromethyl)phenyl)thio)methyl)quinazolin-4(3H)-one CAS 338965-75-6
| CAS No. | 338965-75-6 |
| Molecular Formula | C23H16ClF3N2OS |
| Molecular Weight | 460.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 6-Chloro-3-(o-tolyl)-2-(((3-(trifluoromethyl)phenyl)thio)methyl)quinazolin-4(3H)-one.
6-Chloro-3-(o-tolyl)-2-(((3-(trifluoromethyl)phenyl)thio)methyl)quinazolin-4(3H)-one (CAS 338965-75-6) is a high-purity analytical reference standard with the molecular formula C23H16ClF3N2OS and a molecular weight of 460.90 g/mol.
Structurally, 6-Chloro-3-(o-tolyl)-2-(((3-(trifluoromethyl)phenyl)thio)methyl)quinazolin-4(3H)-one (C23H16ClF3N2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 460.90 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 6-Chloro-3-(o-tolyl)-2-(((3-(trifluoromethyl)phenyl)thio)methyl)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C23H16ClF3N2OS |
| Molecular Weight | 460.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chloro Standards
- 5-Chloro-N-(2,4-dimethoxybenzyl)-2,4-difluoro-N-(thiazol-2-yl)benzenesulfonamide, 97% (CAS 1629041-92-4)
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Recommended Standards
- Tivozanib D6 (CAS CATO-C4X-34001)
- 2-(4-Chlorobenzoyl)-3-[({[3-(trifluoromethyl)phenyl]methyl}sulfanyl)methyl]-1-benzofuran (CAS 400082-36-2)
- 2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(6-chloro-1H-indol-3-yl)propanoic acid (CAS 1219168-45-2)
- 2-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(5-chloro-1h-indol-3-yl)propanoic acid (CAS 1219398-51-2)
- 4-Chloro-N-((dimethylamino)methylene)-2-fluorobenzamide (CAS 2379917-17-4)
- 2-(2,3-Epoxypropoxy)-3-phenylpropiophenone-d (CAS 1189450-87-0)
- 3-(4-Cyclohexylpiperazin-1-yl)propanoic acid (CAS 883548-64-9)
- Ethyl 2-(3-phenylcyclobutyl)acetate (CAS 2120903-56-0)
- 8-(4-Chloro-2-nitrophenoxy)-2-methylquinoline (CAS 852932-31-1)
- 3-[(2,6-Dichlorophenyl)methyl]-1-(3,5-dimethoxyphenyl)-2-methyl-1,4-dihydropyridin-4-one (CAS 339017-20-8)
- 2-Bromo-N-(2-ethoxyphenyl)benzamide (CAS 303991-69-7)
- 6-Chloro-3-(chloromethyl)-5-(difluoromethyl)pyridin-2-amine (CAS 1805922-13-7)
- [9,9'-Bianthracene]-10-carbonitrile (CAS 103266-00-8)
- D-[Phe]6-Semaglutide (CAS CATO-CPTD788633)
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