(2E)-3-[4-(Dimethylamino)phenyl]-2-[5-(2-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile CAS 338966-67-9
| CAS No. | 338966-67-9 |
| Molecular Formula | C22H17FN2OS |
| Molecular Weight | 376.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of (2E)-3-[4-(Dimethylamino)phenyl]-2-[5-(2-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile is closely related to a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies (2E)-3-[4-(Dimethylamino)phenyl]-2-[5-(2-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile (CAS 338966-67-9), a certified reference material (molecular formula C22H17FN2OS, MW 376.45 g/mol) for analytical method development and quality control.
Structurally, (2E)-3-[4-(Dimethylamino)phenyl]-2-[5-(2-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile (C22H17FN2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 376.45 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures (2E)-3-[4-(Dimethylamino)phenyl]-2-[5-(2-fluorobenzoyl)thiophen-2-yl]prop-2-enenitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H17FN2OS |
| Molecular Weight | 376.45 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related E Standards
- Methyl 2-((3-(((dimethylamino)methylene)carbamoyl)piperidin-1-yl)methyl)-3-nitrobenzoate (CAS 865660-27-1)
- 4-[4-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-pyrimidine-2-thiol (CAS 1311278-15-5)
- 4-[3-(6-Dimethylamino-4-trifluoromethyl-pyridin-2-yl)-phenyl]-pyrimidine-2-thiol (CAS 1311279-01-2)
- (E)-3-Dimethylamino-1-[4-(6-dimethylamino-4-trifluoro-methyl-pyridin-2-yl)-phenyl]-but-2-en-1-one (CAS 1311283-92-7)
- 11-(3-(Dimethylamino)prop-1-yn-1-yl)-9-(trifluoromethyl)-6,11-dihydrodibenzo[b,e]thiepin-11-ol (CAS 1956379-79-5)
- 4-[4-(Dimethylamino)benzoyl]-8-propyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326811-26-0)
- 4-(7-(Dimethylamino)-3-m-tolylisoquinolin-1-ylamino)-4-oxobutanoic acid (CAS 1415564-54-3)
- (E)-4-(dimethylamino)-2-(2-((((2-methoxybenzyl)oxy)imino)methyl)-1H-pyrrol-1-yl)nicotinonitrile (CAS 303986-44-9)
Recommended Standards
- (2E)-3-[(Z)-[(2E)-1-(4-Methylphenyl)-3-(3,4,5-trimethoxyphenyl)prop-2-en-1-ylidene]amino]but-2-enenitrile (CAS 866050-02-4)
- (4R,5S)-4,5-Diphenyl-2-(6-phenylpyridin-2-yl)-4,5-dihydrooxazole (CAS 2757082-59-8)
- 4-(1,2,2-Triphenylvinyl)benzoic Acid (CAS 197153-87-0)
- (4S,5S)-4,5-Diphenyl-2-(6-phenylpyridin-2-yl)-4,5-dihydrooxazole (CAS 2757082-57-6)
- 2-(Aminomethyl)-4-chlorophenol hydrobromide (CAS 1235439-85-6)
- 2-Amino-2-(1-(3-chlorophenyl)-3,5-dimethyl-1h-pyrazol-4-yl)acetic acid hydrochloride (CAS 1078161-69-9)
- 6-acetyl-4-ethyl-7-hydroxy-8-methyl-2H-chromen-2-one (CAS 951988-89-9)
- 2-Methyldecane-3,5-dione (CAS 170954-49-1)
- 3,3,5-Trimethyl-1-(2-oxo-2-((3-(trifluoromethyl)phenyl)amino)ethyl)cyclohexane-1-carboxylic acid (CAS 439096-52-3)
- 3,6-Dichloro-N-methoxy-N-methylpyridazine-4-carboxamide (CAS 1211540-71-4)
- 2,3-Dioxo-1,2,3,4-tetrahydroquinoxaline-6-carboxylic acid hydrate (CAS 1255717-69-1)
- Benzo[b]thiophen-2-yl(3-((3-cyclopropyl-1,2,4-oxadiazol-5-yl)methyl)piperidin-1-yl)methanone (CAS 1706316-91-7)
- 4-(4-Bromo-2-chlorophenoxy)aniline (CAS 71258-04-3)
- 551936-17-5 3JX85UOO24 AIM-102 UNII-3JX85UOO24 (4R)-4-(((2R)-2-Amino-3-cyclohexyl-propanoyl)amino)-5-(carboxymethylamino)-5-oxo-pentanoic acid D-Cyclohexylalanine-D-glutamic-glycine tripeptide Glycine, 3-cyclohexyl-D-alanyl-D-alpha-glutamyl- (CAS 551936-17-5)
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