3-(2,4-Dichloro-5-methoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one CAS 338967-89-8
| CAS No. | 338967-89-8 |
| Molecular Formula | C16H12Cl2N2O2S |
| Molecular Weight | 367.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 367.25 g/mol gives 3-(2,4-Dichloro-5-methoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-(2,4-Dichloro-5-methoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one (CAS 338967-89-8), molecular formula C16H12Cl2N2O2S and molecular weight 367.25 g/mol, is a CATO reference standard with documented purity and traceability.
Based on its molecular formula C16H12Cl2N2O2S, 3-(2,4-Dichloro-5-methoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-(2,4-Dichloro-5-methoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl2N2O2S |
| Molecular Weight | 367.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- 2,7-Dichloro-4-methyl-N-phenylquinoline-6-sulfonamide (CAS 1418265-69-6)
- 3-(2,4-Dichloro-5-methoxyphenyl)-6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 339014-86-7)
- Methyl 3-(((5,6-dichloro-1H-benzo[d]imidazol-2-yl)thio)methyl)benzoate (CAS 877628-35-8)
- 4,6-Dichloro-5-nitro-2-[4-(1-piperidinylmethyl)phenyl]pyrimidine (CAS 1353506-55-4)
- 3,4-Dichloro-N-(2-nitrophenyl)benzo[b]thiophene-2-carboxamide (CAS 332382-11-3)
- 4,7-Dichloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one (CAS 2252403-83-9)
- (3-(2,4-Dichloro-5-fluorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-97-7)
- N'-(3,4-Dichloro-1-methyl-1H-pyrazol-5-yl)-N'-methyl-3-(trifluoromethyl)benzohydrazide (CAS 400085-81-6)
Recommended Standards
- 2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-5-(4-methoxyphenyl)-1,3,4-oxadiazole (CAS 332869-35-9)
- 1-(3,4-Dichlorobenzyl)-3-(4-methyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyridin-2(1H)-one (CAS 242797-55-3)
- 3-[(4-Aminophenyl)thio]-1-(2,6-dichlorophenyl)-pyrrolidine-2,5-dione (CAS 931259-01-7)
- 1-(2,4-Dichlorobenzyl)-5-(5-mercapto-4-methyl-4H-1,2,4-triazol-3-yl)pyridin-2(1H)-one (CAS 477853-12-6)
- tert-Butyl (2R,4R)-4-(benzyloxy)-2-(hydroxymethyl)pyrrolidine-1-carboxylate (CAS 869527-82-2)
- N-Me-Ser-OH (CAS 2480-26-4)
- N,3-Dimethylcyclobutan-1-amine hydrochloride (CAS 1445951-89-2)
- Gadoteridol Impurity 3 (CAS 138884-13-6)
- (1-Cyclopropyl-1H-imidazol-2-yl)methanol (CAS 135207-02-2)
- 1-Bromo-3-(ethanesulfonyl)propane (CAS 98137-26-9)
- 1-(4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea (CAS 630124-46-8)
- 1-(4-Chlorobenzyl)-4,6-dimethyl-3-(phenylsulfonyl)pyridin-2(1H)-one (CAS 306977-16-2)
- 1-((4-Fluorophenyl)thio)propan-2-one (CAS 2968-13-0)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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