3-(2,4-Dichloro-5-methoxyphenyl)-6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one CAS 339014-86-7
| CAS No. | 339014-86-7 |
| Molecular Formula | C16H12Cl2N2O2S |
| Molecular Weight | 367.25 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(2,4-Dichloro-5-methoxyphenyl)-6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one (CAS 339014-86-7) is a high-purity analytical reference standard with the molecular formula C16H12Cl2N2O2S and a molecular weight of 367.25 g/mol.
Based on its molecular formula C16H12Cl2N2O2S, 3-(2,4-Dichloro-5-methoxyphenyl)-6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 367.25 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 3-(2,4-Dichloro-5-methoxyphenyl)-6-methyl-2-thioxo-2,3-dihydroquinazolin-4(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H12Cl2N2O2S |
| Molecular Weight | 367.25 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichloro Standards
- 2,7-Dichloro-4-methyl-N-phenylquinoline-6-sulfonamide (CAS 1418265-69-6)
- 3-(2,4-Dichloro-5-methoxyphenyl)-2-(methylthio)quinazolin-4(3H)-one (CAS 338967-89-8)
- Methyl 3-(((5,6-dichloro-1H-benzo[d]imidazol-2-yl)thio)methyl)benzoate (CAS 877628-35-8)
- 4,6-Dichloro-5-nitro-2-[4-(1-piperidinylmethyl)phenyl]pyrimidine (CAS 1353506-55-4)
- 3,4-Dichloro-N-(2-nitrophenyl)benzo[b]thiophene-2-carboxamide (CAS 332382-11-3)
- 4,7-Dichloro-6-fluoro-1-(2-isopropyl-4-methylpyridin-3-yl)pyrido[2,3-d]pyrimidin-2(1H)-one (CAS 2252403-83-9)
- (3-(2,4-Dichloro-5-fluorophenyl)-1-(2-methoxyphenyl)-1H-pyrazol-4-yl)methanol (CAS 618441-97-7)
- N'-(3,4-Dichloro-1-methyl-1H-pyrazol-5-yl)-N'-methyl-3-(trifluoromethyl)benzohydrazide (CAS 400085-81-6)
Recommended Standards
- 3-[(4-Aminophenyl)thio]-1-(2,6-dichlorophenyl)-pyrrolidine-2,5-dione (CAS 931259-01-7)
- 2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-5-(4-methoxyphenyl)-1,3,4-oxadiazole (CAS 332869-35-9)
- 5-(3,4-Dichlorophenyl)-4-(methylsulfonyl)-1-phenyl-1H-pyrazole (CAS 321574-33-8)
- 1-(3,4-Dichlorobenzyl)-3-(4-methyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyridin-2(1H)-one (CAS 242797-55-3)
- 3-(3-Chlorophenyl)-2-cyanopropionic Acid (CAS 1082249-01-1)
- 5-Chloro-1-(3-(trifluoromethoxy)phenyl)pentan-1-one (CAS 898786-25-9)
- Ethyl 5-methyl-1H-pyrrolo[3,2-b]pyridine-2-carboxylate (CAS 1132610-84-4)
- [1,1'-Biphenyl]-3,4',5-tricarbaldehyde (CAS 187281-19-2)
- 1-(4-Bromophenyl)-1H-indazole (CAS 838820-83-0)
- H-Glu(D-Glu-OH)-OH (CAS 6931-86-8)
- 6-Chloro-N-(pyridin-2-ylmethyl)pyridazin-3(2h)-imine (CAS 944780-22-7)
- Ethyl(S)-6-methoxyindoline-2-carboxylatehydrochloride (CAS 1263078-03-0)
- 2,2'-Biquinoline, ruthenium complex (CAS 115403-93-5)
- Semaglutide impurity 22(OtBu-Ste-γGlu(OtBu)-AEEA-AEEA-OH) (CAS 1118767-16-0)
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