3-(4-Benzhydrylpiperazin-1-yl)-5-(trifluoromethyl)picolinonitrile CAS 338968-22-2
| CAS No. | 338968-22-2 |
| Molecular Formula | C24H21F3N4 |
| Molecular Weight | 422.45 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
3-(4-Benzhydrylpiperazin-1-yl)-5-(trifluoromethyl)picolinonitrile (C24H21F3N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
3-(4-Benzhydrylpiperazin-1-yl)-5-(trifluoromethyl)picolinonitrile (CAS 338968-22-2), molecular formula C24H21F3N4 and molecular weight 422.45 g/mol, is a CATO reference standard with documented purity and traceability.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C24H21F3N4 |
| Molecular Weight | 422.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Benzhydrylpiperazin Standards
- 2-(4-Benzhydrylpiperazin-1-yl)-N-(2,4-difluorophenyl)acetamide (CAS 491867-86-8)
- 1-(4-Benzhydrylpiperazin-1-yl)-2-(naphthalen-1-yl)ethan-1-one (CAS 41332-25-6)
- 5-(4-Benzhydrylpiperazin-1-yl)-1,1,1,2,2-pentafluoropentan-3-ol (CAS 691858-23-8)
- (4-Benzhydrylpiperazin-1-yl)(4-(tert-butyl)phenyl)methanone (CAS 312588-66-2)
- 3-(4-Benzhydrylpiperazin-1-yl)-2-(benzo[d]thiazol-2-yl)acrylonitrile (CAS 573931-86-9)
- 2-(4-Benzhydrylpiperazin-1-yl)-1-(4-chlorophenyl)ethan-1-ol (CAS 156810-00-3)
- N-(4-benzhydrylpiperazin-1-yl)-N-(4-chlorophenyl)formamide (CAS 291291-94-6)
- (4-Benzhydrylpiperazin-1-yl)(2-(methylthio)pyridin-3-yl)methanone (CAS 852851-09-3)
Recommended Standards
- 2,7-Dimethoxy-9-((4-nitrobenzyl)sulfinyl)acridine (CAS 827303-17-3)
- 4-((1,3-Dioxoisoindolin-2-yl)methyl)-N-(4-methoxyphenyl)benzenesulfonamide (CAS 955298-15-4)
- 2-(4-(Benzo[d][1,3]dioxol-5-yl)thiazol-2-yl)-3-(3,4,5-trimethoxyphenyl)acrylonitrile (CAS 683250-83-1)
- Diethyl 2,2'-((sulfonylbis(4,1-phenylene))bis(oxy))diacetate (CAS 38775-52-9)
- 3-[1-(Benzenesulfonyl)heptyl]-1,3-oxazolidin-2-one (CAS 861209-18-9)
- N-((tetrahydrofuran-2-yl)methyl)acetamide (CAS 69891-62-9)
- 2,4,5-T-Iso-Octyl Ester (CAS 25168-15-4)
- 4-Bromo-2-ethylbiphenyl (CAS 1809158-13-1)
- 4-Methoxy-1,2-dihydronaphthalene (CAS 84716-82-5)
- N-(2,3-Dimethylquinoxalin-6-yl)benzamide (CAS 28485-67-8)
- 1-Methyl-5-(trimethylsilyl)-1H-pyrazole (CAS 92524-99-7)
- 1-Ethyl-2,3,3-trimethyl-3H-indol-1-ium-5-sulfonate (CAS 146368-07-2)
- 2-(4-Carbamoylbenzenesulfonamido)propanoic acid (CAS 1308973-59-2)
- Tirzepatide(sodium salt) (CAS 2023788-19-2(free base))
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com