3-[4-(4-Methoxyphenyl)piperazin-1-yl]-5-(trifluoromethyl)pyridine-2-carbonitrile CAS 338968-21-1
| CAS No. | 338968-21-1 |
| Molecular Formula | C18H17F3N4O |
| Molecular Weight | 362.35 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, 3-[4-(4-Methoxyphenyl)piperazin-1-yl]-5-(trifluoromethyl)pyridine-2-carbonitrile is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 362.35 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies 3-[4-(4-Methoxyphenyl)piperazin-1-yl]-5-(trifluoromethyl)pyridine-2-carbonitrile (CAS 338968-21-1), a certified reference material (molecular formula C18H17F3N4O, MW 362.35 g/mol) for analytical method development and quality control.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-[4-(4-Methoxyphenyl)piperazin-1-yl]-5-(trifluoromethyl)pyridine-2-carbonitrile meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H17F3N4O |
| Molecular Weight | 362.35 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Methoxyphenyl Standards
- 5-Acetyl-2-(((3-(4-methoxyphenyl)isoxazol-5-yl)methyl)amino)-6-methylnicotinonitrile (CAS 338749-68-1)
- 5-[(3-Methoxyphenyl)methyl]-7-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 860785-75-7)
- 8-Ethyl-4-[2-(4-methoxyphenyl)acetyl]-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid (CAS 1326814-08-7)
- 1-{5-[(2-Methoxyphenyl)methylene]-4-oxo-2-thioxo-1,3-thiazolan-3-yl}dihydro-2,6(1H,3H)-pyridinedione (CAS 477859-29-3)
- 1-{5-[(3-Methoxyphenyl)methylene]-4-oxo-2-thioxo-1,3-thiazolan-3-yl}dihydro-2,6(1H,3H)-pyridinedione (CAS 477859-23-7)
- 4,6-Bis(4-methoxyphenyl)-2-(methylthio)nicotinonitrile (CAS 312757-89-4)
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Recommended Standards
- 3-(5-Methylisoxazol-3-yl)-6-[(1-methyl-1H-1,2,3-triazol-4-yl)methoxy][1,2,4]triazolo[3,4-a]phthalazine (CAS 215874-86-5)
- 4-Methoxy-2-{4-[3-(trifluoromethyl)phenyl]piperazin-1-yl}pyridine-3-carbonitrile (CAS 339102-59-9)
- 3-(3,4-Dimethoxybenzenesulfonyl)-7-hydroxy-2H-chromen-2-one (CAS 866347-90-2)
- 8-Phenyl-7H-purine (CAS 4776-14-1)
- 2-((1S,2S)-2-(2-methoxyphenyl)cyclopropyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2066512-89-6)
- 4-Chloro-6-(4-fluorophenyl)-[1,2,3]triazolo[1,5-a]pyrazine (CAS 1708428-31-2)
- 3-(Difluoromethyl)-1H-pyrrolo[2,3-c]pyridin-4-amine (CAS 2091011-42-4)
- 3-Methoxy-1,5-bis(4-methoxyphenyl)-1H-1,2,4-triazole (CAS 524699-72-7)
- N-(2-Oxo-2-(5-oxo-1,4-diazepan-1-yl)ethyl)-[1,1'-biphenyl]-4-carboxamide (CAS 1787892-81-2)
- (S)-3-Hydroxyisobutyric Acid (CAS 2068-83-9)
- methyl (2R)-2-bromobutanoate (CAS 114438-75-4)
- 4-Ethyl-5-phenyl-1H-pyrazol-3(2H)-one (CAS 642462-43-9)
- 1-(p-Tolyl)-5-(trifluoromethyl)-1H-pyrazole (CAS 1269293-10-8)
- Peptide Impurity 81 TFA (CAS CATO-CPTD788581)
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