(E)-6-chloroimidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime CAS 338976-48-0

Purity 97%+In StockPharmaceutical Standards
CAS No.338976-48-0
Molecular FormulaC13H8Cl3N3OS
Molecular Weight360.65 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(E)-6-chloroimidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime CAS 338976-48-0 chemical structure

Description

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

(E)-6-chloroimidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime (CAS 338976-48-0), molecular formula C13H8Cl3N3OS and molecular weight 360.65 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of (E)-6-chloroimidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime (C13H8Cl3N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

As a certified reference material (CRM), (E)-6-chloroimidazo[2,1-b]thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl) oxime meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC13H8Cl3N3OS
Molecular Weight360.65 g/mol
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3
Sulfur Atoms1

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