N'1-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzene-1-carbohydrazide CAS 265307-85-5
| CAS No. | 265307-85-5 |
| Molecular Formula | C14H8ClF3N4OS |
| Molecular Weight | 372.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including N'1-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzene-1-carbohydrazide.
N'1-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzene-1-carbohydrazide (CAS 265307-85-5), molecular formula C14H8ClF3N4OS and molecular weight 372.75 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, N'1-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzene-1-carbohydrazide (C14H8ClF3N4OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 372.75 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N'1-[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzene-1-carbohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H8ClF3N4OS |
| Molecular Weight | 372.75 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related N Standards
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- Benzyl (2-(8-chloroimidazo[1,5-a]pyrazin-3-yl)cyclohexyl)carbamate (CAS 1956334-88-5)
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Recommended Standards
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- Methyl 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfonyl}-3-(dimethylamino)prop-2-enoate (CAS 1823194-70-2)
- 2-Chloro-3-(2,4-dioxopentan-3-yl)-1,4-dihydroxyanthracene-9,10-dione (CAS 89607-90-9)
- 2-fluoro-5-methoxy-4-nitro-benzoic acid (CAS 1001345-80-7)
- 5-(Dimethylphosphinyl)-2-pyridinecarboxylic acid (CAS 2361959-03-5)
- (R)-2-(2-chloro-3-fluorophenyl)pyrrolidine (CAS 1228571-09-2)
- Ramelteon RC 13 (CAS 178677-89-9)
- 5-Methoxypyridine-2-carboxylic Acid (CAS 29082-92-6)
- 2-(3-Methyl-6-oxo-5-(trifluoromethyl)pyridazin-1(6H)-yl)acetic acid (CAS 1823265-20-8)
- Methyl 4-amino-3-(piperidin-1-yl)benzoate (CAS 1272756-52-1)
- Methyl (E)-3-(naphthalen-2-yl)acrylate (CAS 22837-78-1)
- 7-Chloro-1-benzofuran-2-carbaldehyde (CAS 179728-80-4)
- Semaglutide impurity 26 (CAS CATO-C4X-222626)
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