5-Chloro-1-[(3-chlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide CAS 338977-28-9
| CAS No. | 338977-28-9 |
| Molecular Formula | C13H10Cl2N2O2 |
| Molecular Weight | 297.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-Chloro-1-[(3-chlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide (CAS 338977-28-9) is a high-purity analytical reference standard with the molecular formula C13H10Cl2N2O2 and a molecular weight of 297.14 g/mol.
The molecular framework of 5-Chloro-1-[(3-chlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide (C13H10Cl2N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 5-Chloro-1-[(3-chlorophenyl)methyl]-6-oxo-1,6-dihydropyridine-3-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C13H10Cl2N2O2 |
| Molecular Weight | 297.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 3-(5-Chloro-1-methyl-1H-imidazol-2-yl)-1-(5-chloro-2-hydroxyphenyl)prop-2-en-1-one (CAS 299951-37-4)
- 5-Chloro-1-(4-chlorobenzyl)-2-oxo-1,2-dihydropyridine-3-carboxamide (CAS 338977-27-8)
- Ethyl 3-chloro-6-(4-chlorophenyl)pyridazine-4-carboxylate (CAS 220287-28-5)
- 3-Chloro-4-((3-chlorobenzyl)oxy)benzoic acid (CAS 1002970-32-2)
- 1-(2-Chloro-4-fluorophenyl)-3-(3-chlorophenyl)propan-1-one (CAS 898787-32-1)
- 1-(2-Chloro-4-fluorophenyl)-3-(4-chlorophenyl)propan-1-one (CAS 898788-33-5)
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Recommended Standards
- 5-Cyclopropyl-1-(2,4-dichlorophenyl)-1h-pyrazole-4-carboxylic acid (CAS 241800-51-1)
- 4,6-Dimethylpyrimidin-2-yl 2,4-dichlorobenzoate (CAS 338421-30-0)
- 4-(2,6-Dichlorobenzoyl)-N-methyl-1H-pyrrole-2-carboxamide (CAS 338753-20-1)
- EThyl 7-bromo-1-oxo-3,4-dihydro-2H-naphthalene-2-carboxylate (CAS 914262-72-9)
- 1-(1,4-Dimethyl-1H-pyrazol-3-yl)ethanone (CAS 99644-93-6)
- 4-(2-Oxo-1,3-diazinan-1-yl)benzonitrile (CAS 163918-99-8)
- methyl 6-fluoro-3-methyl-2-oxo-1,3-benzoxazole-7-carboxylate (CAS 2184104-75-2)
- Sodium (±)-3-Hydroxybutyrate-3,4,4,4-d4 (CAS 1219804-68-8)
- Chrysogine (CAS 18326-30-2)
- 3-Phenyl-2-(p-tolylthio)quinoline (CAS 339013-03-5)
- 3-Iodo-4-methyl-5-nitro-1H-indazole (CAS 1167056-16-7)
- Lansoprazole Impurity 26 (5-Hydroxybenzimidazole) (CAS 41292-65-3)
- 5-(Difluoromethyl)-1-(2-methylpropyl)-1h-pyrazole-4-carboxylic acid (CAS 1339834-08-0)
- CGMP Dependent Kinase Inhibitor Peptide (CAS 82801-73-8)
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