5-Chloro-2-oxo-N-phenyl-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide CAS 338977-79-0
| CAS No. | 338977-79-0 |
| Molecular Formula | C20H14ClF3N2O2 |
| Molecular Weight | 406.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 406.79 g/mol gives 5-Chloro-2-oxo-N-phenyl-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
5-Chloro-2-oxo-N-phenyl-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 338977-79-0), molecular formula C20H14ClF3N2O2 and molecular weight 406.79 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 5-Chloro-2-oxo-N-phenyl-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (C20H14ClF3N2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 13.0, corresponding to approximately 13 ring(s) or double-bond equivalent(s). With a molecular weight of 406.79 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H14ClF3N2O2 |
| Molecular Weight | 406.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related Chloro Standards
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-methoxyphenyl)benzamide (CAS 1092343-58-2)
- 1-Benzyl-5-chloro-6-oxo-N-[3-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide (CAS 339024-34-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-phenoxyphenyl)acetamide (CAS 692287-72-2)
- 5-Chloro-2-oxo-N-phenyl-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 338977-52-9)
- 5-Chloro-6-oxo-N-phenyl-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 339024-10-1)
- N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-4-methylbenzamide (CAS 477854-90-3)
- 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)benzo[d]thiazole (CAS 1023553-54-9)
- (2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-methyl-1H-imidazol-5-yl)(morpholino)methanone (CAS 339012-15-6)
Recommended Standards
- N-(4-chlorophenyl)-2-oxo-1-(3-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carboxamide (CAS 338754-72-6)
- N-(4-chlorophenyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-00-2)
- 1-[(4-Chlorophenyl)methyl]-6-oxo-N-[4-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide (CAS 338782-71-1)
- N-(4-chlorophenyl)-6-oxo-1-(4-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 339008-67-2)
- 2,5-Dibromoterephthalic Acid (CAS 13731-82-3)
- 4-Acetylbenzene-1-sulfonyl fluoride (CAS 455-25-4)
- 1-(4-Methyloxan-4-yl)piperazine (CAS 910575-36-9)
- Ethyl 3-amino-4-(3-oxo-1-piperazinyl)benzoate (CAS 1219964-69-8)
- Formic acid - 1,3-dimethyl-5-(2-oxo-2-piperazin-1-ylethyl)imidazolidine-2,4-dione (1:1) (CAS 1922672-09-0)
- 4-(2-Bromoacetamido)benzene-1-sulfonyl fluoride (CAS 21897-05-2)
- 1H-Indole-2,3-dicarboxylic acid (CAS 103030-09-7)
- 3-Chloropyridazine trifluoromethanesulfonate (CAS 1174307-32-4)
- 2-Hydroxy-4’-nitroacetophenone (CAS 64611-67-2)
- Neuropeptide Y (3-36) (porcine) trifluoroacetate salt (CAS 143863-88-1)
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