N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-4-methylbenzamide CAS 477854-90-3
| CAS No. | 477854-90-3 |
| Molecular Formula | C19H14ClF3N4O |
| Molecular Weight | 406.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 406.79 g/mol gives N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-4-methylbenzamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-4-methylbenzamide (CAS 477854-90-3), a certified reference material (molecular formula C19H14ClF3N4O, MW 406.79 g/mol) for analytical method development and quality control.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-4-methylbenzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 406.79 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N-(6-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}pyridin-2-yl)-4-methylbenzamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14ClF3N4O |
| Molecular Weight | 406.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related N Standards
- 4-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-(3-methoxyphenyl)benzamide (CAS 1092343-58-2)
- 1-Benzyl-5-chloro-6-oxo-N-[3-(trifluoromethyl)phenyl]-1,6-dihydropyridine-3-carboxamide (CAS 339024-34-9)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-(2-phenoxyphenyl)acetamide (CAS 692287-72-2)
- 5-Chloro-2-oxo-N-phenyl-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 338977-52-9)
- 5-Chloro-2-oxo-N-phenyl-1-{[4-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carboxamide (CAS 338977-79-0)
- 5-Chloro-6-oxo-N-phenyl-1-(3-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 339024-10-1)
- 2-(4-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)oxy)phenyl)benzo[d]thiazole (CAS 1023553-54-9)
- (2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)-1-methyl-1H-imidazol-5-yl)(morpholino)methanone (CAS 339012-15-6)
Recommended Standards
- N-(4-chlorophenyl)-6-oxo-1-(4-(trifluoromethyl)benzyl)-1,6-dihydropyridine-3-carboxamide (CAS 339008-67-2)
- 1,3-Dibromo-2-iodo-5-nitrobenzene (CAS 98137-96-3)
- N-(4-chlorophenyl)-4-((2-oxo-5-(trifluoromethyl)pyridin-1(2H)-yl)methyl)benzamide (CAS 339025-00-2)
- Afatinib Impurity 66 (CAS CATO-C4X-100666)
- Pyrazolo[1,5-a]pyridin-4-ol, 6-bromo-3-fluoro- (CAS 2770966-34-0)
- (1S,2R,4R)-tert-Butyl 2-(aminomethyl)-3-methylene-7-azabicyclo[2.2.1]heptane-7-carboxylate hydrochloride (CAS 1909288-65-8)
- 2-Methylhexahydro-1H-4,7-epoxyisoindole-1,3(2H)-dione (CAS 7741-81-3)
- 7-amino-1H-pyrazolo[4,3-d]pyrimidine-3-carboxylic acid (CAS 13877-58-2)
- 6,6'-(hydrazine-1,2-diyl)bis(3-chloro-2-methylaniline) (CAS CATO-C3D-262913)
- 2-(6-(tert-Butyl)-8-fluoro-1-oxophthalazin-2(1H)-yl)-6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl acetate (CAS 1242156-76-8)
- Regadenoson Impurity 52 (CAS 1702334-23-3)
- 3422-01-3 N-(tert-Butoxycarbonyl)aniline N-Boc-aniline N-Phenyl-carbamic Acid 1,1-Dimethylethyl Ester tert-Butyl N-Phenylcarbamate tert-Butyl N-Phenylurethane tert-Butyl Phenylcarbamate tert-Butyl-N-phenylcarbamate (CAS 3422-01-3)
- Methyl cyclobutanecarboxylate (CAS 765-85-5)
- Semaglutide impurity 46 (CAS CATO-C4X-222646)
Why CATO?
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