5-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methyl)-4-phenyl-4H-1,2,4-triazole-3-thiol CAS 338979-15-0
| CAS No. | 338979-15-0 |
| Molecular Formula | C19H18ClF3N6S |
| Molecular Weight | 454.90 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
5-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methyl)-4-phenyl-4H-1,2,4-triazole-3-thiol (CAS 338979-15-0), molecular formula C19H18ClF3N6S and molecular weight 454.90 g/mol, is a CATO reference standard with documented purity and traceability.
5-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methyl)-4-phenyl-4H-1,2,4-triazole-3-thiol (C19H18ClF3N6S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 5-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}methyl)-4-phenyl-4H-1,2,4-triazole-3-thiol meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H18ClF3N6S |
| Molecular Weight | 454.90 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 6 |
| Sulfur Atoms | 1 |
Related chloro Standards
- 1-({5-(6-chloro-3-pyridyl)-4-[3-(trifluoromethyl)phenyl]-4H-1,2,4-triazol-3-yl}thio)-3,3-dimethylbutan-2-one (CAS 680217-04-3)
- 2-Chloro-1,5-bis(m-tolyloxy)anthracene-9,10-dione (CAS 61601-43-2)
- 2-Chloro-1,8-bis(m-tolyloxy)anthracene-9,10-dione (CAS 61601-44-3)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-N-((4-methoxyphenyl)carbamothioyl)-1H-pyrrole-2-carboxamide (CAS 338420-75-0)
- 2-(4-(5-Chloro-2-methylphenyl)piperazin-1-yl)-7-(3-fluorophenyl)thieno[3,2-d]pyrimidin-4(1H)-one (CAS 1251599-14-0)
- (2E)-1-[5-({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}methyl)-4,5-dihydro-1,2-oxazol-3-yl]-3-[(4-methoxyphenyl)amino]prop-2-en-1-one (CAS 338422-63-2)
- 4-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]amino}ethyl)-2-(morpholin-4-yl)-3H,4H-pyrido[2,3-b]pyrazin-3-one (CAS 338411-97-5)
- 5-(2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)ethyl)-2-methyl-3-phenyltetrahydro-4H-pyrrolo[3,4-d]isoxazole-4,6(5H)-dione (CAS 317833-32-2)
Recommended Standards
- Ethyl 7-(bis(tert-butoxycarbonyl)amino)-5-chloro-6-methylpyrazolo[1,5-a]pyrimidine-3-carboxylate (CAS 2271471-16-8)
- Empagliflozin Impurity 125 (CAS CATO-C4X-1065125)
- Empagliflozin Impurity 126 (CAS CATO-C4X-1065126)
- Sitaxsentan (CAS 184036-34-8)
- Lithium vanadium oxide, 99.9% (metals basis) (CAS 15060-59-0)
- 4-Chloro-2-Isopropyl-5-Methylphenol (CAS 89-68-9)
- tert-butyl N-(1H-pyrazol-3-yl)carbamate (CAS 952674-76-9)
- Bis(4-methoxyphenyl)phosphinic acid (CAS 20434-05-3)
- Acyclovir-d4 L-Leucinate (CAS 1795785-74-8)
- 5,5-(Butane-1,4-diyl)bis(1,3,4-thiadiazol-2-amine) (CAS 98558-04-4)
- 1-Chloro-2,5-difluoro-3-nitrobenzene (CAS 1805029-24-6)
- Isooctyl isodecyl adipate (CAS 31474-57-4)
- (1S,2R)-rel-2-(6-Bromopyridin-3-yl)cyclopropan-1-amine (CAS 918399-80-1)
- Semaglutide impurity 249 (CAS CATO-C4X-2226249)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com