1-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-(morpholin-4-yl)ethan-1-one CAS 338979-16-1
| CAS No. | 338979-16-1 |
| Molecular Formula | C16H20ClF3N4O2 |
| Molecular Weight | 392.80 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C16H20ClF3N4O2, 1-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-(morpholin-4-yl)ethan-1-one contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 392.80 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
1-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-(morpholin-4-yl)ethan-1-one (CAS 338979-16-1), molecular formula C16H20ClF3N4O2 and molecular weight 392.80 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-{4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}-2-(morpholin-4-yl)ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H20ClF3N4O2 |
| Molecular Weight | 392.80 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 4 |
Related chloro Standards
- N-[2-Chloro-5-(trifluoromethyl)phenyl]-2-[(1-naphthylmethyl)amino]acetamide (CAS 329779-25-1)
- 3-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}-5-[(2Z)-2-(methoxyimino)ethyl]-1,2-thiazole-4-carbonitrile (CAS 338413-08-4)
- 3-Chloro-N-({3-[5-(methylamino)-1,3,4-thiadiazol-2-yl]-4,5-dihydro-1,2-oxazol-5-yl}methyl)-5-(trifluoromethyl)pyridin-2-amine (CAS 477867-49-5)
- 5-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(p-tolyl)-4,5,6,7-tetrahydro-2H-pyrazolo[4,3-c]pyridine (CAS 250714-13-7)
- 5-(5-(((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)amino)methyl)-4,5-dihydroisoxazol-3-yl)-4-methyl-2,4-dihydro-3H-1,2,4-triazole-3-thione (CAS 400082-28-2)
- N'-(2-(4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazin-1-yl)acetyl)-N,N-dimethylformohydrazonamide (CAS 338979-30-9)
- N-(4-chloro-3-nitrophenyl)-2-(4-(4-fluorophenyl)piperazin-1-yl)acetamide (CAS 329779-14-8)
- 4'-[(2-Chloro-5-Methylphenyl)Sulfonylamino]-2,2,2-Trifluoroacetanilide (CAS 64058-75-9)
Recommended Standards
- N-(4-chlorophenyl)-3-(4-fluoro-2-nitrophenoxy)thiophene-2-carboxamide (CAS 303152-71-8)
- Methyl 6-amino-4-(3-chloro-4-methoxyphenyl)-5-cyano-2-(2-methoxy-2-oxoethyl)-4H-pyran-3-carboxylate (CAS 865660-05-5)
- N-(4-chlorophenyl)-4-(4-fluoro-5-methyl-2-nitrophenyl)piperazine-1-carboxamide (CAS 1262222-58-1)
- 6-(4-Chlorophenyl)-1-(3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)-3-methyl-1H-pyrazolo[4,3-d]pyrimidin-7(6H)-one (CAS 89889-80-5)
- 2,3,4,5-Tetrahydro-1H-benzo[c]azepine Hydrochloride (CAS 17724-36-6)
- Lochnerine (CAS 522-47-4)
- H-Asn-Glu-OH (CAS 20917-58-2)
- 4-(Azidomethyl)-2-(4-isopropoxyphenyl)-5-methyl-1,3-oxazole (CAS 1858241-55-0)
- 6-(Naphthalen-1-yl)-2-oxo-1,2,3,6-tetrahydropyrimidine-4-carboxylic acid (CAS 439094-93-6)
- Bicyclohexyl (CAS 92-51-3)
- 1-((1-Methyl-2-oxo-1,2-dihydropyridin-3-yl)sulfonyl)piperidine-4-carboxylic acid (CAS 1708013-18-6)
- 4-Hydroxy-2-methoxybenzyl alcohol, 97% (CAS 119138-29-3)
- Methyl 2-Amino-6-hydroxybenzoate (CAS 64241-01-6)
- Des-Ile12-Aib13-Tirzepatide (CAS CATO-CPTD788960)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com