2-(4-Chloro-2-methylphenoxy)-N-(2,6-difluorophenyl)-2,2-difluoroacetamide CAS 339010-97-8

Purity 97%+In StockPharmaceutical Standards
CAS No.339010-97-8
Molecular FormulaC15H10ClF4NO2
Molecular Weight347.69 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2-(4-Chloro-2-methylphenoxy)-N-(2,6-difluorophenyl)-2,2-difluoroacetamide CAS 339010-97-8 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-(4-Chloro-2-methylphenoxy)-N-(2,6-difluorophenyl)-2,2-difluoroacetamide.

2-(4-Chloro-2-methylphenoxy)-N-(2,6-difluorophenyl)-2,2-difluoroacetamide (CAS 339010-97-8) is a high-purity analytical reference standard with the molecular formula C15H10ClF4NO2 and a molecular weight of 347.69 g/mol.

Based on its molecular formula C15H10ClF4NO2, 2-(4-Chloro-2-methylphenoxy)-N-(2,6-difluorophenyl)-2,2-difluoroacetamide contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 347.69 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC15H10ClF4NO2
Molecular Weight347.69 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)9.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms1

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