1-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethan-1-one CAS 339016-56-7
| CAS No. | 339016-56-7 |
| Molecular Formula | C19H11ClF6N2OS2 |
| Molecular Weight | 496.88 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 1-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
CATO supplies 1-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethan-1-one (CAS 339016-56-7), a certified reference material (molecular formula C19H11ClF6N2OS2, MW 496.88 g/mol) for analytical method development and quality control.
The molecular framework of 1-(5-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methyl}thiophen-2-yl)-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfanyl}ethan-1-one (C19H11ClF6N2OS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C19H11ClF6N2OS2 |
| Molecular Weight | 496.88 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
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Recommended Standards
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- Fenirofibrate O-β-D-Glucuronide (CAS 168844-26-6)
- Losartan Impurity 26 (CAS CATO-C4X-168326)
- 1-(3-(Trifluoromethyl)phenyl)piperidine-4-carboxylic acid (CAS 847407-02-7)
- 3-Chloro-6-iodoimidazo[1,2-a]pyridine-2-carboxylic acid (CAS 900014-87-1)
- n-Benzyl-2-chloro-N-(2,2,2-trifluoroethyl)acetamide (CAS 853574-45-5)
- 2,6-Dimethylpyridine-3-carbaldehyde (CAS 650141-20-1)
- 2,6-Dimethylimidazo[1,2-a]pyrimidine-3-carboxylic acid (CAS 1335052-44-2)
- Ethyl 2,6-diaminoisonicotinate (CAS 98594-42-4)
- 5-Benzoyl-2-(4-chlorophenyl)-1,3-thiazole (CAS 338779-69-4)
- 2-((1-(4-(Methylthio)phenyl)ethyl)amino)propan-1-ol (CAS 1153899-84-3)
- 2-Chloro-1-(4-chloro-3-fluorophenyl)ethan-1-one (CAS 860029-79-4)
- Semaglutide-d5 (CAS CATO-C4X-2226153)
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