2-{[(4-chlorophenyl)methyl]sulfanyl}-4-[(4-chlorophenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline CAS 339019-14-6
| CAS No. | 339019-14-6 |
| Molecular Formula | C21H18Cl2N2S2 |
| Molecular Weight | 433.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-[(4-chlorophenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline.
2-{[(4-chlorophenyl)methyl]sulfanyl}-4-[(4-chlorophenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline (CAS 339019-14-6) is a high-purity analytical reference standard with the molecular formula C21H18Cl2N2S2 and a molecular weight of 433.42 g/mol.
The molecular framework of 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-[(4-chlorophenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline (C21H18Cl2N2S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-{[(4-chlorophenyl)methyl]sulfanyl}-4-[(4-chlorophenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18Cl2N2S2 |
| Molecular Weight | 433.42 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 2 |
Related chlorophenyl Standards
- 2-{[(2-chlorophenyl)methyl]sulfanyl}-4-[(4-chlorophenyl)sulfanyl]-5,6,7,8-tetrahydroquinazoline (CAS 339019-41-9)
- (E)-[(4-Chlorophenyl)methoxy]({4-[(4-chlorophenyl)sulfanyl]-3-nitrophenyl}methylidene)amine (CAS 338396-08-0)
- 4-[(1E)-3-(4-Chlorophenyl)-3-oxoprop-1-en-1-yl]phenyl 4-chlorobenzene-1-sulfonate (CAS 331460-95-8)
- {5-[(4-chlorophenyl)sulfanyl]-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl}methyl 2,2-dichloroacetate (CAS 318239-60-0)
- 4-Chlorophenyl 4-((3,4-dichloro-1-methyl-1H-pyrazol-5-yl)oxy)benzenesulfonate (CAS 303996-51-2)
- 5-(4-Chlorophenyl)-N-(2,5-dimethoxyphenyl)-1-phenyl-1H-pyrazole-3-carboxamide (CAS 477712-41-7)
- (4-((4-Chlorophenyl)sulfonyl)quinolin-3-yl)(thiomorpholino)methanone (CAS 1111014-26-6)
- 3-(4-((2-Chlorophenyl)sulfonyl)piperazin-1-yl)-6-(3,5-dimethyl-1H-pyrazol-1-yl)pyridazine (CAS 1013835-29-4)
Recommended Standards
- 3,3'-(Isoindoline-1,3-diylidene)bis(quinoline-2,4(1H,3H)-dione) (CAS 85223-06-9)
- 5-Methyl-12-oxo-N-[4-(trifluoromethoxy)phenyl]-5H,5aH,6H,7H,8H,9H,10H,12H-azepino[2,1-b]quinazoline-3-carboxamide (CAS 1775503-17-7)
- Methyl 3-((tert-butoxycarbonyl)amino)-5-(2,2,2-trifluoro-1-((methylsulfonyl)oxy)ethyl)thiophene-2-carboxylate (CAS 2163771-83-1)
- 5-Ethyl-11-oxo-N-[4-(trifluoromethoxy)phenyl]-5H,5aH,6H,7H,8H,9H,11H-pyrido[2,1-b]quinazoline-3-carboxamide (CAS 1574560-89-6)
- N-(2-Chlorobenzyl)-2-((4-ethyl-5-(3-methoxy-1-methyl-1H-pyrazol-4-yl)-4H-1,2,4-triazol-3-yl)thio)acetamide (CAS 1014095-15-8)
- 1-Benzyl-1H-pyrazol-3(2H)-one (CAS 21074-40-8)
- Ethyl (2-chloroethyl)carbamate (CAS 6329-26-6)
- 1-(2,4-Difluoro-3-(trifluoromethyl)phenyl)ethanone (CAS 1202679-46-6)
- 7-Bromo-6-chloro-8-fluoroquinolin-4(1H)-one (CAS 2349394-43-8)
- 2-Ethyl-4-pyridinecarboxamide (CAS 3376-95-2)
- Lusutrombopag Impurity 3 (CAS CATO-C4X-20843)
- 6-(4-Methoxyphenyl)-1,3,5-triazine-2,4-diamine (CAS 30354-91-7)
- {spiro[2.3]hexan-1-yl}methanol (CAS 1515534-09-4)
- Semaglutide Impurity 185 (CAS CATO-C4X-2226185)
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