5-(2,4-Dichlorobenzoyl)-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine CAS 339023-15-3
| CAS No. | 339023-15-3 |
| Molecular Formula | C16H8Cl4N2OS |
| Molecular Weight | 418.12 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 5-(2,4-Dichlorobenzoyl)-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine.
5-(2,4-Dichlorobenzoyl)-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine (CAS 339023-15-3), molecular formula C16H8Cl4N2OS and molecular weight 418.12 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 5-(2,4-Dichlorobenzoyl)-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine (C16H8Cl4N2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 5-(2,4-Dichlorobenzoyl)-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H8Cl4N2OS |
| Molecular Weight | 418.12 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Dichlorobenzoyl Standards
- 5-(3,4-Dichlorobenzoyl)-N-(3,4-dichlorophenyl)-1,3-thiazol-2-amine (CAS 339023-11-9)
- 2-(4-(2,4-Dichlorobenzoyl)-1-oxa-4,8-diazaspiro[4.5]Decan-8-yl)pyrimidine-5-carbonitrile (CAS 400086-93-3)
- 4-[5-(3,4-Dichlorobenzoyl)-3-(pyridin-2-yl)thiophen-2-yl]morpholine (CAS 339023-23-3)
- N'-(2,4-Dichlorobenzoyl)-1-ethyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbohydrazide (CAS 302904-34-3)
- 5-(2,4-Dichlorobenzoyl)-7-(trifluoromethyl)-1H,2H,3H,3aH,4H,5H-pyrrolo[1,2-a]quinoxaline (CAS 861206-93-1)
- 3-(2,4-Dichlorobenzoyl)-5-(4-hydroxy-3-methoxybenzylidene)-2-thioxoimidazolidin-4-one (CAS 554423-02-8)
- (E)-4-((5-((((2,4-dichlorobenzoyl)oxy)imino)methyl)pyridin-2-yl)oxy)benzonitrile (CAS 339014-84-5)
- 2-(2,4-Dichlorobenzoyl)-3-phenoxy-5-(trifluoromethyl)pyridine (CAS 306977-33-3)
Recommended Standards
- (E)-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methoxy}({[3-chloro-5-(trifluoromethyl)pyridin-2-yl]methylidene})amine (CAS 400081-12-1)
- 4,4'-(Pentane-1,2-diyl)bis(2-bromo-1-fluorobenzene) (CAS 2504201-61-8)
- N'-(2,6-bis(trifluoromethyl)pyridin-4-yl)-2,6-dichlorobenzohydrazide (CAS 240115-92-8)
- 2-(Bromomethyl)-2-(2-chloro-4-(4-chlorophenoxy)phenyl)-4-methyl-1,3-dioxolane (CAS 873012-43-2)
- 2-((4-Oxospiro[chromane-2,1'-cyclohexan]-6-yl)oxy)acetic acid (CAS 135111-35-2)
- 3-((3-Chloropyridin-4-yl)methyl)pyrrolidin-3-ol (CAS 1479230-02-8)
- 2-(5-Chloro-2,4-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane (CAS 2121512-49-8)
- 5-Amino-2-ethyl-7-(pyridin-4-yl)-1,7-dihydropyrano[2,3-d]imidazole-6-carbonitrile (CAS 374612-98-3)
- 3-(2-Bromopyridin-3-yl)propanoic acid (CAS 1784983-11-4)
- Fluorescent Brightener 210 (CAS 28950-61-0)
- 2-((4-Chlorophenyl)thio)-1-cyclopropylethan-1-one (CAS 1344305-58-3)
- 3-Chloro-2-fluoro-4-(trifluoromethyl)aniline (CAS 1807135-05-2)
- 4-(Bromomethyl)-3-methyloxazolidine (CAS 63221-92-1)
- Peptide 438 (CAS CATO-CPTD788438)
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